SCHEMBL756825

SCHEMBL756825

CC1(C2[C@@H](F)[C@@H](Oc3cc(N4CCc5nc(C(N)=O)ccc54)ncn3)CCN2C(=O)O)CC1

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 20/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3510203 0.80 GPR119 (0.38) GPR119
SCHEMBL756824 0.78 GPR119 (0.38) GPR119
SCHEMBL298683 0.78 GPR119 (0.38) GPR119
SCHEMBL299860 0.74 GPR119 (0.39) GPR119
SCHEMBL756571 0.74 GPR119 (0.39) GPR119
SCHEMBL757863 0.71 GPR119 (0.37) GPR119
SCHEMBL299177 0.71 GPR119 (0.33) GPR119
SCHEMBL759313 0.70 GPR119 (0.31) GPR119
SCHEMBL757959 0.66 GPR119 (0.48) GPR119
SCHEMBL1768278 0.66 GPR119 (0.32) GPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120052130-A1 GPR 119 MODULATORS PFIZER INC. 2012-03-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120052130-A1 GPR 119 MODULATORS GPR119, GPR39, GPR65 GPR119 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.