SCHEMBL7574341

SCHEMBL7574341

COC(=O)c1cc(OC(C)=O)c2cc(OC)cc(OC)c2c1

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.48
PKM P14618 2/20 0.48
NPC1 O15118 1/20 0.48
RAB9A P51151 1/20 0.48
KMT2A Q03164 6/20 0.47
MAPT P10636 2/20 0.44
TSHR P16473 1/20 0.44
TNFSF11 O14788 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
BACE1 P56817 1/20 0.41
CNR2 P34972 1/20 0.40
USP2 O75604 1/20 0.40
CYP3A4 P08684 1/20 0.40
MAPK1 P28482 1/20 0.40
MEN1 O00255 3/20 0.39
POLB P06746 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30076482 1.00 SMN1; SMN2 (0.48) SMN1; SMN2PKMNPC1RAB9AKMT2A
SCHEMBL3401603 0.89 RAB9A (0.43) SMN1; SMN2PKMNPC1RAB9AKMT2A
SCHEMBL6481401 0.87 NPC1 (0.42) SMN1; SMN2PKMNPC1RAB9AKMT2A
SCHEMBL7568873 0.82 XDH (0.51) SMN1; SMN2KMT2AMAPTCA1CA2
SCHEMBL7789471 0.82 SMN1; SMN2 (0.48) SMN1; SMN2PKMNPC1RAB9AKMT2A
SCHEMBL29089553 0.80 KMT2A (0.48) SMN1; SMN2PKMNPC1RAB9AKMT2A
SCHEMBL13018859 0.79 MEN1 (0.46) SMN1; SMN2PKMNPC1RAB9AKMT2A
SCHEMBL6131966 0.78 PKM (0.52) SMN1; SMN2PKMNPC1RAB9AKMT2A
SCHEMBL4798665 0.77 SMN1; SMN2 (0.52) SMN1; SMN2PKMNPC1RAB9AKMT2A
SCHEMBL28366507 0.77 PKM (0.54) SMN1; SMN2PKMNPC1RAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115490577-A Preparation method and application of 5, 7-dimethoxy-1-naphthol 阜阳欣奕华制药科技有限公司 2022-12-20 CN claimed
CN-115490577-A Preparation method and application of 5, 7-dimethoxy-1-naphthol 阜阳欣奕华制药科技有限公司 2022-12-20 CN disclosed
CN-115490577-A Preparation method and application of 5, 7-dimethoxy-1-naphthol 阜阳欣奕华制药科技有限公司 2022-12-20 CN disclosed
EP-0984929-B1 NAPHTHOPYRAN DERIVATIVES, COMPOSITIONS AND (CO)POLYMER MATRICES CONTAINING THE SAME CORNING SA (FR) 2002-09-11 EP disclosed
US-6399791-B1 PHOTOCHROMISM CORNING S.A. (FR) 2002-06-04 US disclosed
EP-0984929-A1 NAPHTHOPYRAN DERIVATIVES, COMPOSITIONS AND (CO)POLYMERS MATRICES CONTAINING SAME CORNING INCORPORATED (US) 2000-03-15 EP disclosed
EP-0984929-A4 NAPHTHOPYRAN DERIVATIVES, COMPOSITIONS AND (CO)POLYMERS MATRICES CONTAINING SAME CORNING INC (US) 2000-03-15 EP disclosed
WO-1998042663-A1 NAPHTHOPYRAN DERIVATIVES, COMPOSITIONS AND (CO)POLYMERS MATRICES CONTAINING SAME CORNING INCORPORATED (US) 1998-10-01 WO disclosed