Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.51 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.51 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | ALPL | P05186 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8797975 | 0.88 | EPHX2 (0.56) | EPHX2KCNQ3KCNQ2HPGDRECQL | |
| SCHEMBL8801191 | 0.76 | CNR2 (0.38) | HPGDKMT2AMEN1POLBNPC1 | |
| SCHEMBL27508818 | 0.74 | HPGD (0.63) | EPHX2KCNQ3KCNQ2HPGDRECQL | |
| SCHEMBL4516287 | 0.72 | HCRTR1 (0.42) | KMT2AMEN1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL26686541 | 0.71 | EPHX2 (0.60) | EPHX2KCNQ3KCNQ2HPGDRECQL | |
| SCHEMBL1803010 | 0.71 | P2RX7 (0.78) | EPHX2RECQLKMT2AMEN1NPC1 | |
| SCHEMBL5233494 | 0.70 | SMN1; SMN2 (0.53) | EPHX2HPGDRECQLKMT2AMEN1 | |
| SCHEMBL30685737 | 0.70 | TDP1 (0.63) | HPGDKMT2AMEN1POLBP2RX7 | |
| SCHEMBL27340684 | 0.70 | ALDH1A1 (0.46) | KCNQ3KCNQ2HPGDRAB9AALDH1A1 | |
| SCHEMBL8798277 | 0.69 | NPC1 (0.41) | KMT2AMEN1NPC1RAB9AP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915876-A1 | TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS | American Cyanamid Company (US) | 1999-05-19 | — | — | EP | disclosed |
| WO-1997049707-A1 | TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS | AMERICAN CYANAMID COMPANY (US) | 1997-12-31 | — | — | WO | disclosed |