Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 4/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7567740 | 0.83 | KMT2A (0.42) | NPC1MAPK8MAPK9MAPK10KMT2A | |
| SCHEMBL7570572 | 0.80 | NAMPT (0.55) | NPC1KMT2AL3MBTL1MEN1RAB9A | |
| SCHEMBL7505880 | 0.77 | SGMS2 (0.45) | NPC1KMT2AL3MBTL1MEN1RAB9A | |
| SCHEMBL5237758 | 0.72 | RAB9A (0.43) | NPC1KMT2AL3MBTL1MEN1RAB9A | |
| SCHEMBL8797776 | 0.70 | KMT2A (0.52) | NPC1MAPK8KMT2AL3MBTL1MEN1 | |
| SCHEMBL7569274 | 0.69 | EPHX2 (0.51) | NPC1KMT2AMEN1RAB9AP2RX7 | |
| SCHEMBL8801191 | 0.69 | CNR2 (0.38) | NPC1KMT2AL3MBTL1MEN1RAB9A | |
| SCHEMBL7493834 | 0.69 | KMT2A (0.65) | NPC1KMT2AL3MBTL1MEN1RAB9A | |
| SCHEMBL8313292 | 0.68 | KMT2A (0.41) | MAPK8KMT2A | |
| SCHEMBL1307479 | 0.68 | MEN1 (0.54) | NPC1MAPK8KMT2AMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811008-A1 | BICYCLIC BENZAZEPINE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | American Cyanamid Company (US) | 1997-12-10 | — | — | EP | disclosed |