Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | CNKSR1 | Q969H4 | 3/20 | 0.50 |
| ▸ | AKT1 | P31749 | 2/20 | 0.50 |
| ▸ | PLK1 | P53350 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7573848 | 0.88 | ALDH1A1 (0.60) | ALDH1A1LMNAHPGDKMT2AMEN1 | |
| SCHEMBL7577661 | 0.83 | ALDH1A1 (0.49) | ALDH1A1LMNAHPGDKMT2AMEN1 | |
| SCHEMBL9930699 | 0.79 | CCR2 (0.60) | ALDH1A1LMNAHPGDKMT2AMEN1 | |
| SCHEMBL1653221 | 0.79 | MEN1 (0.49) | ALDH1A1LMNAHPGDKMT2AMEN1 | |
| SCHEMBL2354908 | 0.78 | MEN1 (0.53) | ALDH1A1LMNAHPGDKMT2AMEN1 | |
| SCHEMBL1653948 | 0.77 | ALDH1A1 (0.52) | ALDH1A1LMNAHPGDKMT2AMEN1 | |
| SCHEMBL7570489 | 0.77 | LMNA (0.52) | ALDH1A1LMNAHPGDKMT2AMAPT | |
| SCHEMBL1652707 | 0.76 | CNKSR1 (0.47) | ALDH1A1LMNAHPGDKMT2AMEN1 | |
| SCHEMBL12783356 | 0.76 | MEN1 (0.49) | ALDH1A1LMNAHPGDKMT2AMEN1 | |
| SCHEMBL1653275 | 0.76 | HIF1A (0.51) | ALDH1A1LMNAHPGDKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |