Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS4 | O75173 | 8/20 | 0.51 |
| ▸ | MMP13 | P45452 | 6/20 | 0.51 |
| ▸ | MMP2 | P08253 | 12/20 | 0.48 |
| ▸ | MMP3 | P08254 | 5/20 | 0.48 |
| ▸ | MMP9 | P14780 | 8/20 | 0.47 |
| ▸ | MMP1 | P03956 | 3/20 | 0.47 |
| ▸ | MMP7 | P09237 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7509479 | 0.92 | CTSL (0.48) | ADAMTS4MMP13MMP2MMP3MMP9 | |
| SCHEMBL7515533 | 0.91 | ADAMTS4 (0.56) | ADAMTS4MMP13MMP2MMP3MMP9 | |
| SCHEMBL7509896 | 0.87 | MMP13 (0.61) | ADAMTS4MMP13MMP2MMP3MMP9 | |
| SCHEMBL6769963 | 0.78 | MMP2 (0.60) | ADAMTS4MMP13MMP2MMP3MMP9 | |
| SCHEMBL7497120 | 0.78 | MMP2 (0.60) | ADAMTS4MMP13MMP2MMP3MMP9 | |
| SCHEMBL6742817 | 0.77 | ADAMTS4 (0.60) | ADAMTS4MMP13MMP2MMP3MMP9 | |
| SCHEMBL6773478 | 0.76 | CTSL (0.46) | ADAMTS4MMP13MMP2MMP3MMP9 | |
| SCHEMBL5573278 | 0.75 | CTSL (0.54) | ADAMTS4MMP13MMP2MMP3MMP9 | |
| SCHEMBL12808878 | 0.75 | MMP2 (0.76) | ADAMTS4MMP13MMP2MMP3MMP9 | |
| SCHEMBL6739724 | 0.74 | ADAMTS4 (0.63) | ADAMTS4MMP13MMP2MMP3MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165501-A1 | ALKENYL- AND ALKYNYL-CONTAINING METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2002-01-02 | — | — | EP | disclosed |
| US-6197770-B1 | ENZYME INHIBITORS; ANTIARTHRITIC AGENTS; BONE DISORDERS | THE PROCTER & GAMBLE CO. | 2001-03-06 | — | — | US | disclosed |
| WO-2000051975-A1 | ALKENYL- AND ALKYNYL-CONTAINING METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2000-09-08 | — | — | WO | disclosed |