Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MCOLN2 | Q8IZK6 | 1/20 | 0.53 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.53 |
| ▸ | MCOLN1 | Q9GZU1 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7588944 | 0.86 | ALDH1A1 (0.56) | MEN1KMT2APOLBALDH1A1GAA | |
| SCHEMBL7586724 | 0.85 | NPC1 (0.68) | MEN1KMT2APOLBHTTALDH1A1 | |
| SCHEMBL2246137 | 0.85 | POLB (0.70) | MEN1KMT2APOLBHTTALDH1A1 | |
| SCHEMBL3380247 | 0.84 | POLB (0.68) | MEN1KMT2APOLBHTTALDH1A1 | |
| SCHEMBL7571620 | 0.83 | POLB (0.68) | MEN1KMT2APOLBHTTALDH1A1 | |
| SCHEMBL7572319 | 0.83 | POLB (0.68) | MEN1KMT2APOLBHTTALDH1A1 | |
| SCHEMBL789616 | 0.83 | KEAP1 (0.72) | MEN1KMT2APOLBHTTALDH1A1 | |
| SCHEMBL2835167 | 0.82 | POLB (0.66) | MEN1KMT2APOLBHTTALDH1A1 | |
| SCHEMBL23555160 | 0.80 | ALDH1A1 (0.71) | MEN1KMT2APOLBALDH1A1GAA | |
| SCHEMBL1037267 | 0.80 | EDNRA (0.56) | MEN1KMT2APOLBALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |