Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | CCR2 | P41597 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23555160 | 0.90 | ALDH1A1 (0.71) | ALDH1A1MAPTLMNAUSP2POLB | |
| SCHEMBL7571609 | 0.86 | MAPT (0.54) | ALDH1A1CCR2MAPTLMNAPOLB | |
| SCHEMBL7572140 | 0.86 | RECQL (0.69) | ALDH1A1MAPTLMNAPOLBGAA | |
| SCHEMBL7570459 | 0.86 | MEN1 (0.66) | ALDH1A1POLBL3MBTL1SMN1; SMN2GAA | |
| SCHEMBL7579848 | 0.82 | GAA (0.50) | ALDH1A1CCR2MAPTLMNAUSP2 | |
| SCHEMBL7596280 | 0.82 | CCR2 (0.56) | ALDH1A1CCR2MAPTLMNAPOLB | |
| SCHEMBL7597807 | 0.82 | CCR2 (0.71) | CCR2LMNA | |
| SCHEMBL13343627 | 0.81 | MAPT (0.53) | ALDH1A1CCR2MAPTLMNAUSP2 | |
| SCHEMBL7590023 | 0.80 | CCR2 (0.51) | ALDH1A1CCR2MAPTLMNASMN1; SMN2 | |
| SCHEMBL13995037 | 0.80 | PGR (0.69) | ALDH1A1MAPTLMNAPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |