Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 11/20 | 0.41 |
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 2/20 | 0.39 |
| ▸ | CTSK | P43235 | 2/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | REN | P00797 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.38 |
| ▸ | MMP3 | P08254 | 4/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7543803 | 0.94 | CTSK (0.43) | MMP1CTSSCTSKRENMMP3 | |
| SCHEMBL7571304 | 0.92 | CTSK (0.41) | CTSSCTSKRENCTSLCTSB | |
| SCHEMBL7569173 | 0.92 | CTSK (0.41) | MMP1CTSSCTSKRENCTSL | |
| SCHEMBL7571661 | 0.91 | CTSK (0.40) | MMP1CTSSCTSKRENHDAC3 | |
| SCHEMBL7541309 | 0.90 | ANPEP (0.40) | MMP1FPR2CTSSCTSKANPEP | |
| SCHEMBL7541782 | 0.89 | ANPEP (0.40) | MMP1FPR2CTSSCTSKANPEP | |
| SCHEMBL7544754 | 0.89 | FPR2 (0.49) | MMP1FPR2ANPEPRENHDAC3 | |
| SCHEMBL7545704 | 0.89 | HDAC3 (0.46) | MMP1FPR2CTSSCTSKANPEP | |
| SCHEMBL7569100 | 0.88 | CTSK (0.38) | MMP1FPR2CTSSCTSKREN | |
| SCHEMBL7567398 | 0.87 | ANPEP (0.38) | MMP1FPR2CTSSCTSKANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |