Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 4/20 | 0.43 |
| ▸ | CTSS | P25774 | 2/20 | 0.43 |
| ▸ | CTSL | P07711 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | REN | P00797 | 1/20 | 0.38 |
| ▸ | MME | P08473 | 3/20 | 0.38 |
| ▸ | ACE | P12821 | 2/20 | 0.38 |
| ▸ | CPA1 | P15085 | 2/20 | 0.38 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 3/20 | 0.36 |
| ▸ | MMP9 | P14780 | 2/20 | 0.36 |
| ▸ | MMP7 | P09237 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | ECE1 | P42892 | 5/20 | 0.36 |
| ▸ | MMP3 | P08254 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7569173 | 0.96 | CTSK (0.41) | CTSKCTSSCTSLGAAMAPT | |
| SCHEMBL7571304 | 0.96 | CTSK (0.41) | CTSKCTSSCTSLGAAMAPT | |
| SCHEMBL7571661 | 0.95 | CTSK (0.40) | CTSKCTSSCTSLGAAMAPT | |
| SCHEMBL7570635 | 0.94 | MMP1 (0.41) | CTSKCTSSCTSLRENMMP9 | |
| SCHEMBL7569100 | 0.93 | CTSK (0.38) | CTSKCTSSCTSLMAPTREN | |
| SCHEMBL7546039 | 0.91 | CTSK (0.43) | CTSKCTSSCTSLGAAMAPT | |
| SCHEMBL7540886 | 0.90 | CTSK (0.43) | CTSKCTSSCTSLGAAMAPT | |
| SCHEMBL7546445 | 0.88 | GAA (0.44) | CTSKCTSSGAAMAPTHPGD | |
| SCHEMBL7565424 | 0.87 | CTSK (0.40) | CTSKCTSSCTSLGAAMAPT | |
| SCHEMBL7567257 | 0.87 | CTSK (0.40) | CTSKCTSSCTSLGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |