Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | CACNA1F | O60840 | 4/20 | 0.41 |
| ▸ | CACNA1D | Q01668 | 4/20 | 0.41 |
| ▸ | CACNA1S | Q13698 | 4/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7570466 | 0.86 | MAPT (0.45) | ALDH1A1TDP1MAPTMEN1LMNA | |
| SCHEMBL6136665 | 0.83 | ALDH1A1 (0.48) | ALDH1A1MAPTMEN1KMT2ANPSR1 | |
| SCHEMBL7571050 | 0.82 | LMNA (0.40) | TDP1LMNAMAPK1SMN1; SMN2CYP2C9 | |
| SCHEMBL7574293 | 0.82 | LTB4R2 (0.40) | ALDH1A1TDP1LMNAKMT2AHTT | |
| SCHEMBL7573230 | 0.81 | TSHR (0.45) | ALDH1A1TDP1MEN1LMNAKMT2A | |
| SCHEMBL7571829 | 0.81 | GAA (0.44) | ALDH1A1TDP1MAPTMEN1KMT2A | |
| SCHEMBL7573703 | 0.79 | LTB4R2 (0.44) | ALDH1A1NPSR1HTTCYP2D6 | |
| SCHEMBL7567342 | 0.77 | CETP (0.40) | ALDH1A1TDP1MAPTMEN1LMNA | |
| SCHEMBL27552975 | 0.76 | GAA (0.47) | ALDH1A1TDP1CACNA1FCACNA1DCACNA1S | |
| SCHEMBL8599745 | 0.76 | ESR1 (0.39) | ALDH1A1TDP1MAPTMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998022494-A9 | METHODS AND COMPOUNDS FOR INHIBITING β-AMYLOID PEPTIDE RELEASE AND/OR SYNTHESIS | — | 1998-08-20 | — | — | WO | disclosed |