Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 6/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7571050 | 0.86 | LMNA (0.40) | RAB9ALMNAHPGDNPC1SMN1; SMN2 | |
| SCHEMBL7573703 | 0.85 | LTB4R2 (0.44) | LTB4R2HPGDALDH1A1HTTFAAH | |
| SCHEMBL7569876 | 0.85 | FAAH (0.39) | RAB9ALMNAHPGDNPC1SMN1; SMN2 | |
| SCHEMBL7573230 | 0.85 | TSHR (0.45) | RAB9ALMNAHPGDNPC1SMN1; SMN2 | |
| SCHEMBL7571829 | 0.85 | GAA (0.44) | SMN1; SMN2ALDH1A1TSHRTDP1L3MBTL1 | |
| SCHEMBL7879014 | 0.84 | ALDH1A1 (0.38) | RAB9ALMNAHPGDNPC1SMN1; SMN2 | |
| SCHEMBL7570696 | 0.82 | ALDH1A1 (0.43) | LMNASMN1; SMN2ALDH1A1HTTTDP1 | |
| SCHEMBL7567342 | 0.81 | CETP (0.40) | RAB9ALMNAHPGDNPC1SMN1; SMN2 | |
| SCHEMBL6136582 | 0.81 | ALDH1A1 (0.42) | LTB4R2RAB9ALMNANPC1SMN1; SMN2 | |
| SCHEMBL8599745 | 0.80 | ESR1 (0.39) | RAB9ALMNAHPGDNPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998022494-A9 | METHODS AND COMPOUNDS FOR INHIBITING β-AMYLOID PEPTIDE RELEASE AND/OR SYNTHESIS | — | 1998-08-20 | — | — | WO | disclosed |