SCHEMBL6865176

SCHEMBL6865176

CCNC(O)c1c(N)ccc(N)c1C(C)O

nearest known ligand 0.32

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
TSHR P16473 1/20 0.32
MAPK1 P28482 1/20 0.32
ADRB2 P07550 1/20 0.32
ADRB1 P08588 1/20 0.32
ADRB3 P13945 1/20 0.32
SIGMAR1 Q99720 1/20 0.32
GCGR P47871 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2037027 0.79 ALDH1A1 (0.34) CYP1A2CYP3A4TSHRMAPK1ADRB2
SCHEMBL7572535 0.78 GCGR (0.30) GCGR
SCHEMBL7571572 0.71 HIF1A (0.32) ADRB2
SCHEMBL11415039 0.71 GCGR (0.33) GCGR
SCHEMBL505952 0.70 TDP1 (0.34) CYP3A4TSHR
SCHEMBL6274688 0.69 CYP1A2 (0.31) CYP1A2CYP3A4TSHRMAPK1ADRB2
SCHEMBL6241966 0.68 ALDH1A1 (0.44) CYP1A2TSHRMAPK1
SCHEMBL6272267 0.67 CYP1A2 (0.32) CYP1A2CYP3A4TSHRMAPK1ADRB2
SCHEMBL4852014 0.66 CYP3A4 (0.43) CYP1A2CYP3A4TSHRMAPK1ADRB1
SCHEMBL7089983 0.64 PDE2A (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6800097-B2 FOR DYEING KERATIN FIBERS; HAIR DYES WELLA AKTIENGESELLSCHAFT (DE) 2004-10-05 US disclosed
US-20030070241-A1 Substituted 2-aminoalkyl-1,4-Diaminobenzene compounds and oxidation dye precursor compositions containing same WELLA INTERNATIONAL OPERATIONS SWITZERLAND SARL (CH) 2003-04-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030070241-A1 Substituted 2-aminoalkyl-1,4-Diaminobenzene compounds and oxidation dye precursor compositions containing same DDT, ALDH7A1, DDC CYP1A2 141/4885CYP3A4 475/4885TSHR 4363/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.