SCHEMBL7089983

SCHEMBL7089983

CC(O)c1ccc(N)c(C(C)O)c1N

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PDE2A O00408 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2037027 0.81 ALDH1A1 (0.34)
SCHEMBL6122863 0.81 CYP3A4 (0.31) PDE2A
SCHEMBL6751624 0.77 LMNA (0.31)
SCHEMBL1464678 0.76 CYP3A4 (0.39)
SCHEMBL6241966 0.74 ALDH1A1 (0.44)
SCHEMBL7571572 0.73 HIF1A (0.32)
SCHEMBL4852014 0.72 CYP3A4 (0.43)
SCHEMBL992768 0.71 CD44 (0.44)
SCHEMBL9791485 0.71 POLB (0.39) PDE2A
SCHEMBL505952 0.71 TDP1 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3096735-A1 GRADUAL HAIRCOLOR COMPOSITIONS AND METHODS OF USING THE SAME Combe International Ltd. (US) 2016-11-30 EP claimed
CN-105916482-A Gradual hair color compositions and methods of use thereof 酷姆国际公司 2016-08-31 CN claimed
WO-2015112789-A1 GRADUAL HAIRCOLOR COMPOSITIONS AND METHODS OF USING THE SAME COMBE INTERNATIONAL LTD. (US) 2015-07-30 WO claimed
EP-3096735-A1 GRADUAL HAIRCOLOR COMPOSITIONS AND METHODS OF USING THE SAME Combe International Ltd. (US) 2016-11-30 EP disclosed
CN-105916482-A Gradual hair color compositions and methods of use thereof 酷姆国际公司 2016-08-31 CN disclosed
WO-2015112787-A1 COMPOSITIONS FOR COLORING HAIR INCLUDING MULTI-LAMELLAR EMULSION SYSTEMS AND METHODS OF MAKING THE SAME COMBE INTERNATIONAL LTD. (US) 2015-07-30 WO disclosed
WO-2015112789-A1 GRADUAL HAIRCOLOR COMPOSITIONS AND METHODS OF USING THE SAME COMBE INTERNATIONAL LTD. (US) 2015-07-30 WO disclosed
WO-2003075871-A1 METHOD OF GRADUAL PERMANENT COLORING OF HAIR UNILEVER PLC (GB) 2003-09-18 WO disclosed