Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 7/20 | 0.56 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.55 |
| ▸ | GHSR | Q92847 | 2/20 | 0.44 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.44 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.44 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | NAMPT | P43490 | 2/20 | 0.40 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.39 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.39 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL7095796 | 0.94 | ADRB3 (0.61) | ADRB3ADRB1GHSRTPSAB1TPSD1 | |
| SCHEMBL7095127 | 0.91 | ADRB3 (0.62) | ADRB3ADRB1GHSRTPSAB1TPSD1 | |
| SCHEMBL7094653 | 0.87 | ADRB3 (0.57) | ADRB3ADRB1TPSAB1TPSD1TPSG1 | |
| Formic Acid SCHEMBL7570814 | 0.86 | GHSR (0.54) | ADRB3ADRB1GHSRPLA2G2A | |
| Formic Acid SCHEMBL7236466 | 0.84 | ADRB3 (0.49) | ADRB3ADRB1TPSAB1TPSD1TPSG1 | |
| Formic Acid SCHEMBL7096055 | 0.84 | TPSAB1 (0.54) | ADRB3ADRB1TPSAB1TPSD1TPSG1 | |
| Formic Acid SCHEMBL7095073 | 0.83 | TPSAB1 (0.47) | ADRB3ADRB1TPSAB1TPSD1TPSG1 | |
| Formic Acid SCHEMBL7096866 | 0.82 | ADRB3 (0.60) | ADRB3ADRB1CA2CA9NAMPT | |
| SCHEMBL7091850 | 0.81 | TPSAB1 (0.53) | ADRB3ADRB1TPSAB1TPSD1TPSG1 | |
| Formic Acid SCHEMBL7095348 | 0.81 | ADRB3 (0.61) | ADRB3ADRB1TPSAB1TPSD1TPSG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6451814-B1 | SUBSTITUTED 4-((4-AMINO-5-HYDROXYPHENYL)-OXY-)PIPERIDINE ANALOGS; METABOLIC DISORDERS; ANTIDIABETIC AGENTS; ATHERO-SCLEROSIS, GASTROINTESTINAL DISORDERS, GLAUCOMA, NEUROGENETIC INFLAMMATION, OCULAR HYPERTENSION AND FREQUENT URINATION | WYETH | 2002-09-17 | — | — | US | disclosed |
| US-20020028832-A1 | Heterocyclic beta-3 adrenergic receptor agonists | AMERICAN HOME PRODUCTS CORPORATION (US) | 2002-03-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020028832-A1 | Heterocyclic beta-3 adrenergic receptor agonists | ADRB1, ADRB3, ADRB2 | ADRB3 2/4885ADRB1 1/4885GHSR 88/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.