Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PC1 | P35575 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 2/20 | 0.32 |
| ▸ | ACHE | P22303 | 2/20 | 0.32 |
| ▸ | BACE1 | P56817 | 2/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.31 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.31 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7573298 | 0.88 | CA2 (0.38) | G6PC1LMNASMN1; SMN2 | |
| SCHEMBL7573303 | 0.88 | CA2 (0.38) | G6PC1LMNASMN1; SMN2 | |
| SCHEMBL7581324 | 0.85 | CHRM5 (0.44) | MAPTLMNANPC1RAB9AGAA | |
| SCHEMBL7581260 | 0.81 | LMNA (0.38) | MAPTLMNARAB9AGAABCHE | |
| SCHEMBL7573242 | 0.81 | MEN1 (0.37) | G6PC1MAPTMAOBLMNANPC1 | |
| SCHEMBL7573246 | 0.81 | MEN1 (0.37) | G6PC1MAPTMAOBLMNANPC1 | |
| SCHEMBL7571301 | 0.80 | CTDSP1 (0.40) | MAPTLMNANPC1RAB9ABCHE | |
| SCHEMBL7571297 | 0.80 | CTDSP1 (0.40) | MAPTLMNANPC1RAB9ABCHE | |
| SCHEMBL7575394 | 0.80 | GRIN1 (0.36) | MAPTLMNANPC1RAB9AGAA | |
| SCHEMBL7579060 | 0.79 | G6PC1 (0.43) | G6PC1MAPTMAOBLMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0810199-B1 | Method for producing propargylamine compounds | SUMITOMO CHEMICAL CO (JP) | 2002-09-25 | — | — | EP | disclosed |
| US-5756769-A | Method for producing propargylamine compounds | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 1998-05-26 | — | — | US | disclosed |
| EP-0810199-A1 | Method for producing propargylamine compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-12-03 | — | — | EP | disclosed |