Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HNF4A | P41235 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | DHODH | Q02127 | 4/20 | 0.46 |
| ▸ | PARP1 | P09874 | 2/20 | 0.46 |
| ▸ | FABP3 | P05413 | 1/20 | 0.45 |
| ▸ | FABP4 | P15090 | 1/20 | 0.45 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.45 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27416309 | 0.88 | PARP1 (0.61) | ALDH1A1DHODHPARP1BCAT2NPC1 | |
| SCHEMBL902623 | 0.78 | ALDH1A1 (0.66) | ALDH1A1HSD17B10DHODHNR4A1NR4A2 | |
| SCHEMBL7569359 | 0.77 | ALDH1A1 (0.51) | HNF4AALDH1A1HSD17B10DHODHPARP1 | |
| SCHEMBL5459806 | 0.77 | ALDH1A1 (0.50) | ALDH1A1HSD17B10PARP1NR4A1NR4A2 | |
| SCHEMBL7571768 | 0.77 | ALB (0.50) | ALDH1A1HSD17B10DHODHNR4A1NR4A2 | |
| SCHEMBL7567221 | 0.77 | TSHR (0.52) | ALDH1A1HSD17B10FABP3FABP4FABP5 | |
| SCHEMBL7568792 | 0.77 | ALDH1A1 (0.46) | ALDH1A1HSD17B10DHODHPARP1FABP4 | |
| SCHEMBL7407371 | 0.74 | HNF4A (0.73) | HNF4AALDH1A1HSD17B10FABP3FABP4 | |
| SCHEMBL7566755 | 0.74 | TERT (0.46) | ALDH1A1HSD17B10PARP1NR4A1NR4A2 | |
| SCHEMBL20291543 | 0.74 | ALDH1A1 (0.52) | ALDH1A1HSD17B10MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1116285-C | Bis(acridinecarboxamide) and Bis(phenazinecarboxamide) as antitumour agents | XENOVA LTD (GB) | 2003-07-30 | — | — | CN | disclosed |
| EP-0934278-B1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LTD (GB) | 2002-09-04 | — | — | EP | disclosed |
| US-6114332-A | BACTERICIDES | XENOVA LIMITED (GB) | 2000-09-05 | — | — | US | disclosed |
| CN-1240430-A | Bis(acridinecarboxamide) and Bis(phenazinecarboxamide) as antitumour agents | XENOVA LTD (GB) | 2000-01-05 | — | — | CN | disclosed |
| EP-0934278-A1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LIMITED (GB) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998017650-A1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LIMITED (GB) | 1998-04-30 | — | — | WO | disclosed |