Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 2/20 | 0.59 |
| ▸ | CCR1 | P32246 | 1/20 | 0.58 |
| ▸ | CCR4 | P51679 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | KDM1A | O60341 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | MMP1 | P03956 | 1/20 | 0.54 |
| ▸ | MMP2 | P08253 | 1/20 | 0.54 |
| ▸ | MMP9 | P14780 | 1/20 | 0.54 |
| ▸ | MMP8 | P22894 | 1/20 | 0.54 |
| ▸ | MMP13 | P45452 | 1/20 | 0.54 |
| ▸ | SLC20A2 | Q08357 | 1/20 | 0.53 |
| ▸ | SLC20A1 | Q8WUM9 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.53 |
| ▸ | CLK1 | P49759 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7572611 | 0.90 | CCR2 (0.55) | CCR2CCR1CCR4MEN1KMT2A | |
| SCHEMBL7573862 | 0.88 | MCL1 (0.61) | CCR2CCR1CCR4MEN1KMT2A | |
| SCHEMBL7578393 | 0.86 | SLC20A2 (0.64) | CCR2CCR1CCR4KMT2AGAA | |
| SCHEMBL17340529 | 0.86 | CCR2 (0.55) | CCR2CCR1CCR4MEN1KMT2A | |
| SCHEMBL10238207 | 0.84 | CCR2 (0.55) | CCR2CCR1CCR4MEN1KMT2A | |
| SCHEMBL7592771 | 0.83 | MEN1 (0.74) | CCR2MEN1KMT2AGAACA1 | |
| SCHEMBL10238210 | 0.83 | CCR2 (0.57) | CCR2CCR1CCR4MEN1KMT2A | |
| SCHEMBL14434571 | 0.83 | ALDH1A1 (0.65) | CCR2CCR1CCR4MEN1KMT2A | |
| SCHEMBL9931068 | 0.83 | CCR2 (0.67) | CCR2 | |
| SCHEMBL10581966 | 0.82 | CCR2 (0.62) | CCR2CCR1CCR4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |