Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC20A2 | Q08357 | 1/20 | 0.64 |
| ▸ | SLC20A1 | Q8WUM9 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | PGR | P06401 | 2/20 | 0.54 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.54 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | CCR2 | P41597 | 2/20 | 0.51 |
| ▸ | PLAU | P00749 | 1/20 | 0.51 |
| ▸ | PLAT | P00750 | 1/20 | 0.51 |
| ▸ | CCR1 | P32246 | 1/20 | 0.51 |
| ▸ | CCR4 | P51679 | 1/20 | 0.51 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.50 |
| ▸ | AR | P10275 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.50 |
| ▸ | SQSTM1 | Q13501 | 1/20 | 0.49 |
| ▸ | AXL | P30530 | 1/20 | 0.49 |
| ▸ | CCR9 | P51686 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7572438 | 0.87 | SLC20A2 (0.63) | SLC20A2SLC20A1LMNAPGRKEAP1 | |
| SCHEMBL7572164 | 0.86 | CCR2 (0.59) | SLC20A2SLC20A1LMNAPGRGAA | |
| SCHEMBL7567283 | 0.85 | PLAU (0.62) | SLC20A2SLC20A1LMNAPGRKEAP1 | |
| SCHEMBL7572611 | 0.84 | CCR2 (0.55) | SLC20A2SLC20A1LMNAGAAKMT2A | |
| SCHEMBL14434571 | 0.84 | ALDH1A1 (0.65) | SLC20A2SLC20A1LMNAGAAKMT2A | |
| SCHEMBL7573862 | 0.80 | MCL1 (0.61) | SLC20A2SLC20A1LMNAGAAKMT2A | |
| SCHEMBL7593595 | 0.80 | CCR9 (0.62) | CCR2CCR9 | |
| SCHEMBL7568102 | 0.80 | PTPN2 (0.52) | SLC20A2SLC20A1LMNAPGRKMT2A | |
| SCHEMBL7572540 | 0.79 | KMT2A (0.58) | LMNAKEAP1NFE2L2GAAKMT2A | |
| SCHEMBL10238207 | 0.78 | CCR2 (0.55) | SLC20A2SLC20A1LMNAGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |