Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | PTAFR | P25105 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL321300 | 0.86 | SMN1; SMN2 (0.35) | HTR1ADRD2HTR2AHTR2CDRD3 | |
| SCHEMBL44249 | 0.81 | LMNA (0.36) | NPC1RAB9ASMN1; SMN2TP53NFKB1 | |
| SCHEMBL16491630 | 0.81 | HDAC6 (0.35) | HTR1ADRD2HTR2AHTR2CDRD3 | |
| SCHEMBL14872074 | 0.79 | NAAA (0.52) | NPC1RAB9ASMN1; SMN2TP53NFKB1 | |
| SCHEMBL7950954 | 0.78 | SMN1; SMN2 (0.34) | HTR1ADRD2HTR2AHTR2CDRD3 | |
| SCHEMBL900949 | 0.78 | SMN1; SMN2 (0.36) | HTR1ADRD2HTR2AHTR2CDRD3 | |
| SCHEMBL14868085 | 0.78 | NPC1 (0.45) | NPC1RAB9ASMN1; SMN2TP53NFKB1 | |
| SCHEMBL15493502 | 0.78 | SMN1; SMN2 (0.37) | HTR1ADRD2HTR2AHTR2CDRD3 | |
| SCHEMBL7950952 | 0.77 | TP53 (0.34) | HTR1AHTR2ADRD3NPC1RAB9A | |
| SCHEMBL17161322 | 0.77 | RGS12 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002061045-A2 | SIMPLIFIED METHOD FOR INDEXING AND DETERMINING THE RELATIVE CONCENTRATION OF EXPRESSED MESSENGER RNAS | DIGITAL GENE TECHNOLOGIES, INC. (US) | 2002-08-08 | — | — | WO | claimed |
| US-20020012922-A1 | Simplified method for indexing and determining the relative concentration of expressed messenger RNAs | NEUROME, INC. | 2002-01-31 | — | — | US | claimed |
| WO-2001083696-A2 | METHODS FOR RAPID ISOLATION AND SEQUENCE DETERMINATION OF GENE-SPECIFIC SEQUENCES | DIGITAL GENE TECH INC (US) | 2001-11-08 | — | — | WO | claimed |
| WO-2002061045-A2 | SIMPLIFIED METHOD FOR INDEXING AND DETERMINING THE RELATIVE CONCENTRATION OF EXPRESSED MESSENGER RNAS | DIGITAL GENE TECHNOLOGIES, INC. (US) | 2002-08-08 | — | — | WO | disclosed |
| US-20020012922-A1 | Simplified method for indexing and determining the relative concentration of expressed messenger RNAs | NEUROME, INC. | 2002-01-31 | — | — | US | disclosed |
| WO-2001083696-A2 | METHODS FOR RAPID ISOLATION AND SEQUENCE DETERMINATION OF GENE-SPECIFIC SEQUENCES | DIGITAL GENE TECH INC (US) | 2001-11-08 | — | — | WO | disclosed |