Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 2/20 | 0.31 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | DRD3 | P35462 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8741061 | 0.86 | SMN1; SMN2 (0.32) | TP53LMNARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL7950954 | 0.84 | SMN1; SMN2 (0.34) | LMNARAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL7572269 | 0.77 | HTR1A (0.36) | TP53LMNARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL4396451 | 0.70 | ALDH1A1 (0.33) | SMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL24274155 | 0.69 | HPGD (0.38) | LMNAALDH1A1MAPTHPGDKDM4E | |
| SCHEMBL30031578 | 0.67 | ALDH1A1 (0.33) | SMN1; SMN2ALDH1A1KMT2ADRD3 | |
| SCHEMBL346020 | 0.67 | ALDH1A1 (0.33) | SMN1; SMN2ALDH1A1KMT2ADRD3 | |
| SCHEMBL9136872 | 0.67 | HDAC3 (0.33) | RAB9ASMN1; SMN2NPC1ALDH1A1KMT2A | |
| SCHEMBL9136880 | 0.67 | ALDH1A1 (0.34) | LMNASMN1; SMN2NPC1ALDH1A1KMT2A | |
| SCHEMBL3483237 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001083696-A2 | METHODS FOR RAPID ISOLATION AND SEQUENCE DETERMINATION OF GENE-SPECIFIC SEQUENCES | DIGITAL GENE TECH INC (US) | 2001-11-08 | — | — | WO | claimed |