Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28191716 | 0.67 | RXFP1 (0.50) | ALDH1A1KDM4EHPGDHSD17B10TSHR | |
| SCHEMBL4779721 | 0.65 | MAPT (0.57) | ALDH1A1KDM4EHPGDTSHRGAA | |
| SCHEMBL30364396 | 0.65 | MAPT (0.57) | ALDH1A1KDM4EHPGDTSHRGAA | |
| SCHEMBL4910288 | 0.64 | CDC25B (0.60) | ALDH1A1KDM4EHPGDHSD17B10TSHR | |
| SCHEMBL27827028 | 0.64 | ALDH1A1 (0.65) | ALDH1A1KDM4EHPGDHSD17B10TSHR | |
| SCHEMBL3654282 | 0.64 | PKM (0.53) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| SCHEMBL21065586 | 0.64 | TSHR (0.53) | ALDH1A1KDM4EHSD17B10TSHRGAA | |
| SCHEMBL3654283 | 0.64 | PKM (0.53) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| SCHEMBL28191717 | 0.63 | GAA (0.61) | ALDH1A1GAALMNASMN1; SMN2 | |
| SCHEMBL11875164 | 0.63 | NPC1 (0.60) | ALDH1A1KDM4EHPGDHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0894084-B1 | CINNAMIC ACID DERIVATIVES AND THEIR USE AS INTEGRIN ANTAGONISTS | SEARLE & CO (US) | 2002-06-26 | — | — | EP | claimed |