Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SNCA | P37840 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7669953 | 0.83 | ALDH1A1 (0.38) | ARALDH1A1KMT2AMAPTSIGMAR1 | |
| SCHEMBL1552966 | 0.71 | KMT2A (0.49) | ARALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL30936706 | 0.71 | MAPT (0.59) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| SCHEMBL761128 | 0.70 | TSHR (0.45) | ALDH1A1LMNANPC1RAB9ATSHR | |
| SCHEMBL4747223 | 0.70 | TRPM8 (0.42) | ALDH1A1HTTLMNANPC1RAB9A | |
| SCHEMBL2504679 | 0.69 | AOC3 (0.41) | ALDH1A1HTTNPC1RAB9ATSHR | |
| SCHEMBL182883 | 0.69 | CA2 (0.35) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| Hydrochloric Acid SCHEMBL1881838 | 0.68 | AOC3 (0.40) | ALDH1A1KMT2AMEN1HTTLMNA | |
| SCHEMBL976922 | 0.67 | ALDH1A1 (0.39) | ALDH1A1KMT2AMEN1TDP1LMNA | |
| SCHEMBL7258846 | 0.67 | CA2 (0.40) | ALDH1A1KMT2AMEN1HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002040467-A1 | COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-05-23 | — | — | WO | disclosed |