Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7575469 | 0.83 | BDKRB1 (0.44) | SOAT1HTTGSK3ALTB4R2BDKRB1 | |
| SCHEMBL7570389 | 0.83 | HTT (0.40) | SOAT1HTTGSK3AADORA1ADORA3 | |
| SCHEMBL7575457 | 0.83 | SOAT1 (0.40) | SOAT1HTTGSK3AADORA1ADORA3 | |
| SCHEMBL7570660 | 0.82 | PTGER1 (0.41) | SOAT1BDKRB1 | |
| SCHEMBL7572573 | 0.74 | SOAT1 (0.36) | SOAT1HTTGSK3AADORA1ADORA3 | |
| SCHEMBL4609709 | 0.72 | LTB4R2 (0.60) | HTTPOLBLTB4R2ALDH1A1HPGD | |
| SCHEMBL1309175 | 0.72 | ALDH1A1 (0.58) | HTTPOLBALDH1A1HPGDTSHR | |
| SCHEMBL5485083 | 0.72 | NPC1 (0.44) | ALDH1A1HPGDKDM4EGAANPC1 | |
| SCHEMBL8081241 | 0.70 | BDKRB1 (0.44) | SOAT1GSK3ALTB4R2BDKRB1 | |
| SCHEMBL443650 | 0.70 | LTB4R2 (0.65) | LTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0685470-B1 | Benzene derivatives and pharmaceutical composition | KUREHA CHEMICAL IND CO LTD (JP) | 2002-09-11 | — | — | EP | disclosed |
| EP-0685470-A2 | Benzene derivatives and pharmaceutical composition | Kureha Chemical Industry Co., Ltd. (JP) | 1995-12-06 | — | — | EP | disclosed |