Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.76 |
| ▸ | TTR | P02766 | 2/20 | 0.53 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.47 |
| ▸ | TUBB | P07437 | 1/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.47 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.47 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.47 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.47 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.47 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.47 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.47 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | P4HB | P07237 | 3/20 | 0.47 |
| ▸ | FBP1 | P09467 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL75729 | 1.00 | ENPP2 (0.76) | ENPP2TTRTUBB4ATUBBTUBA3C | |
| SCHEMBL6016 | 0.87 | ENPP2 (1.00) | ENPP2P4HBALDH1A1CA12CA2 | |
| SCHEMBL1260529 | 0.82 | FBP1 (0.59) | ENPP2KDM4EP4HBFBP1HDAC2 | |
| SCHEMBL8699093 | 0.82 | FBP1 (0.59) | ENPP2KDM4EP4HBFBP1HDAC2 | |
| SCHEMBL2400920 | 0.82 | TTR (0.71) | ENPP2TTRTUBB4ATUBBTUBA3C | |
| SCHEMBL2400914 | 0.82 | TTR (0.71) | ENPP2TTRTUBB4ATUBBTUBA3C | |
| SCHEMBL1687898 | 0.82 | FBP1 (0.59) | ENPP2KDM4EP4HBFBP1HDAC2 | |
| SCHEMBL13799049 | 0.82 | FBP1 (0.59) | ENPP2KDM4EP4HBFBP1HDAC2 | |
| SCHEMBL21574805 | 0.82 | FBP1 (0.59) | ENPP2KDM4EP4HBFBP1HDAC2 | |
| SCHEMBL1687911 | 0.82 | FBP1 (0.59) | ENPP2KDM4EP4HBFBP1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2150176-B1 | IMPLANTABLE CONCENTRATION SENSOR AND DEVICE | ST JUDE MEDICAL (SE) | 2016-04-27 | — | — | EP | disclosed |
| US-8569502-B2 | Quaternary nitrogen heterocyclic compounds for detecting aqueous monosaccharides in physiological fluids | Geddes, Chris (US) | 2013-10-29 | — | — | US | disclosed |
| US-8569502-B2 | Quaternary nitrogen heterocyclic compounds for detecting aqueous monosaccharides in physiological fluids | Geddes, Chris (US) | 2013-10-29 | — | — | US | disclosed |
| US-20130210158-A1 | QUATERNARY NITROGEN HETEROCYCLIC COMPOUNDS FOR DETECTING AQUEOUS MONOSACCHARIDES IN PHYSIOLOGICAL FLUIDS | GEDDES, CHRIS, DR. | 2013-08-15 | — | — | US | disclosed |
| US-20130210158-A1 | QUATERNARY NITROGEN HETEROCYCLIC COMPOUNDS FOR DETECTING AQUEOUS MONOSACCHARIDES IN PHYSIOLOGICAL FLUIDS | GEDDES, CHRIS, DR. | 2013-08-15 | — | — | US | disclosed |
| US-8338602-B2 | Quaternary nitrogen heterocyclic compounds for detecting aqueous monosaccharides in physiological fluids | UNIVERSITY OF MARYLAND, BALTIMORE COUNTY (US) | 2012-12-25 | — | — | US | disclosed |
| US-8338602-B2 | Quaternary nitrogen heterocyclic compounds for detecting aqueous monosaccharides in physiological fluids | UNIVERSITY OF MARYLAND, BALTIMORE COUNTY (US) | 2012-12-25 | — | — | US | disclosed |
| US-8131333-B2 | Ophthalmic sensor | EYESENSE AG (CH) | 2012-03-06 | — | — | US | disclosed |
| EP-1671118-B1 | CYANIDE SENSING COMPOUNDS AND USES THEREOF | UNIV MARYLAND (US) | 2011-11-02 | — | — | EP | disclosed |
| EP-1671118-B1 | CYANIDE SENSING COMPOUNDS AND USES THEREOF | UNIV MARYLAND (US) | 2011-11-02 | — | — | EP | disclosed |
| US-20070020182-A1 | Quaternary nitrogen heterocyclic compounds for detecting aqueous monosaccharides in physiological fluids | GEDDES, CHRIS, DR. | 2007-01-25 | — | — | US | disclosed |
| US-20070020182-A1 | Quaternary nitrogen heterocyclic compounds for detecting aqueous monosaccharides in physiological fluids | GEDDES, CHRIS, DR. | 2007-01-25 | — | — | US | disclosed |
| EP-1671118-A2 | CYANIDE SENSING COMPOUNDS AND USES THEREOF | University of Maryland Biotechnology Institute (US) | 2006-06-21 | — | — | EP | disclosed |
| EP-1654543-A1 | OPHTHALMIC SENSOR | Novartis AG (CH) | 2006-05-10 | — | — | EP | disclosed |
| EP-1644330-A2 | QUATERNARY NITROGEN HETEROCYCLIC COMPOUNDS FOR DETECTING AQUEOUS MONOSACCHARIDES IN PHYSIOLOGICAL FLUIDS | UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE (US) | 2006-04-12 | — | — | EP | disclosed |
| US-20050158245-A1 | Fluorescent probes for saccharrides | LAKOWICZ JOSEPH R (US) | 2005-07-21 | — | — | US | disclosed |
| WO-2005029033-A2 | CYANIDE SENSING COMPOUNDS AND USES THEREOF | UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE (US) | 2005-03-31 | — | — | WO | disclosed |
| WO-2005015237-A1 | OPHTHALMIC SENSOR | NOVARTIS AG (CH) | 2005-02-17 | — | — | WO | disclosed |
| WO-2005000109-A2 | QUATERNARY NITROGEN HETEROCYCLIC COMPOUNDS FOR DETECTING AQUEOUS MONOSACCHARIDES IN PHYSIOLOGICAL FLUIDS | UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE (US) | 2005-01-06 | — | — | WO | disclosed |
| US-20040087842-A1 | Fluorescent probes for saccharrides | LAKOWICZ JOSEPH R (US) | 2004-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050158245-A1 | Fluorescent probes for saccharrides | H1-3, H1-0, H1-2 | ENPP2 1838/4885TTR 1997/4885TUBB4A 1016/4885 |
| US-20130210158-A1 | QUATERNARY NITROGEN HETEROCYCLIC COMPOUNDS FOR DETECTING AQUEOUS MONOSACCHARIDES IN PHYSIOLOGICAL FLUIDS | SLC5A1, NISCH, SLC5A2 | ENPP2 2619/4885TTR 287/4885TUBB4A 3401/4885 |
| US-20040087842-A1 | Fluorescent probes for saccharrides | ST6GAL1, SLC5A1, CA6 | ENPP2 1962/4885TTR 1711/4885TUBB4A 2062/4885 |
| US-20070020182-A1 | Quaternary nitrogen heterocyclic compounds for detecting aqueous monosaccharides in physiological fluids | SLC5A1, NISCH, SLC5A2 | ENPP2 2619/4885TTR 287/4885TUBB4A 3401/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.