Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | VCAM1 | P19320 | 10/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | PGK1 | P00558 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7545601 | 0.81 | ALDH3A1 (0.46) | ALDH1A1MAPK1MAPTSMN1; SMN2TSHR | |
| SCHEMBL11879757 | 0.76 | CYP19A1 (0.44) | MAPT | |
| SCHEMBL6084022 | 0.75 | VCAM1 (0.44) | ALDH1A1MAPK1MAPTTSHRVCAM1 | |
| SCHEMBL28808502 | 0.74 | MAPK1 (0.53) | ALDH1A1MAPK1MAPTLMNASMN1; SMN2 | |
| SCHEMBL12051112 | 0.73 | ALDH1A1 (0.42) | ALDH1A1MAPK1MAPTLMNASMN1; SMN2 | |
| SCHEMBL18360144 | 0.72 | KEAP1 (0.38) | ALDH1A1SMN1; SMN2TSHRTDP1 | |
| SCHEMBL12051117 | 0.72 | ALDH1A1 (0.41) | ALDH1A1MAPK1MAPTLMNASMN1; SMN2 | |
| SCHEMBL2477068 | 0.72 | TSHR (0.52) | ALDH1A1MAPK1TSHRVCAM1CYP3A4 | |
| SCHEMBL29653309 | 0.72 | TSHR (0.52) | ALDH1A1MAPK1TSHRVCAM1CYP3A4 | |
| SCHEMBL18360143 | 0.71 | ALDH1A1 (0.38) | ALDH1A1PGK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0970040-B1 | METHOD FOR PRODUCING N-CARBOXYALKYL-3-FLUORO-4-DIALKYLAMINONILINES | CLARIANT GMBH (DE) | 2002-06-12 | — | — | EP | claimed |
| EP-0970040-A1 | METHOD FOR PRODUCING N-CARBOXYALKYL-3-FLUORO-4-DIALKYLAMINONILINES | Clariant GmbH (DE) | 2000-01-12 | — | — | EP | claimed |
| US-5917037-A | Process for the preparation of n-carboxyalkyl-3-fluoro-4-dialkylaminoanilines | CLARIANT GMBH (DE) | 1999-06-29 | — | — | US | claimed |
| US-5917036-A | Process for the preparation of N-carboxyalkyl-3-fluoro-4-dialkylaminoanilines | CLARIANT GMBH (DE) | 1999-06-29 | — | — | US | claimed |
| WO-1998040348-A1 | METHOD FOR PRODUCING N-CARBOXYALKYL-3-FLUORO-4-DIALKYLAMINONILINES | CLARIANT GMBH (DE) | 1998-09-17 | — | — | WO | claimed |
| EP-0863129-A1 | Process for the preparation of N-carboxyalkyl-3-fluoro-4-diaklylaminoanilines | Clariant GmbH (DE) | 1998-09-09 | — | — | EP | claimed |
| JP-11001463-A | — | — | None | — | — | JP | disclosed |
| EP-0970040-B1 | METHOD FOR PRODUCING N-CARBOXYALKYL-3-FLUORO-4-DIALKYLAMINONILINES | CLARIANT GMBH (DE) | 2002-06-12 | — | — | EP | disclosed |
| EP-0970040-B1 | METHOD FOR PRODUCING N-CARBOXYALKYL-3-FLUORO-4-DIALKYLAMINONILINES | CLARIANT GMBH (DE) | 2002-06-12 | — | — | EP | disclosed |
| EP-0970040-A1 | METHOD FOR PRODUCING N-CARBOXYALKYL-3-FLUORO-4-DIALKYLAMINONILINES | Clariant GmbH (DE) | 2000-01-12 | — | — | EP | disclosed |
| EP-0970040-A1 | METHOD FOR PRODUCING N-CARBOXYALKYL-3-FLUORO-4-DIALKYLAMINONILINES | Clariant GmbH (DE) | 2000-01-12 | — | — | EP | disclosed |
| US-5990309-A | 2-chloro-5-fluoro-4-morpholinonitrobenzene and 2-chloro-5-fluoro-4-morpholinoaniline | CLARIANT GMBH (DE) | 1999-11-23 | — | — | US | disclosed |
| US-5990309-A | 2-chloro-5-fluoro-4-morpholinonitrobenzene and 2-chloro-5-fluoro-4-morpholinoaniline | CLARIANT GMBH (DE) | 1999-11-23 | — | — | US | disclosed |
| US-5917037-A | Process for the preparation of n-carboxyalkyl-3-fluoro-4-dialkylaminoanilines | CLARIANT GMBH (DE) | 1999-06-29 | — | — | US | disclosed |
| US-5917037-A | Process for the preparation of n-carboxyalkyl-3-fluoro-4-dialkylaminoanilines | CLARIANT GMBH (DE) | 1999-06-29 | — | — | US | disclosed |
| JP-H111463-A | PRODUCTION OF N-CARBOXYALKYL-3-FLUORO-4-DIALKYLAMINOANILINE | CLARIANT GMBH | 1999-01-06 | — | — | JP | disclosed |
| WO-1998040348-A1 | METHOD FOR PRODUCING N-CARBOXYALKYL-3-FLUORO-4-DIALKYLAMINONILINES | CLARIANT GMBH (DE) | 1998-09-17 | — | — | WO | disclosed |
| WO-1998040348-A1 | METHOD FOR PRODUCING N-CARBOXYALKYL-3-FLUORO-4-DIALKYLAMINONILINES | CLARIANT GMBH (DE) | 1998-09-17 | — | — | WO | disclosed |
| EP-0863129-A1 | Process for the preparation of N-carboxyalkyl-3-fluoro-4-diaklylaminoanilines | Clariant GmbH (DE) | 1998-09-09 | — | — | EP | disclosed |
| EP-0863129-A1 | Process for the preparation of N-carboxyalkyl-3-fluoro-4-diaklylaminoanilines | Clariant GmbH (DE) | 1998-09-09 | — | — | EP | disclosed |