Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7148626 | 0.99 | — | — | |
| Hydrochloric Acid SCHEMBL6444703 | 0.75 | ALDH1A1 (0.33) | — | |
| Hydrochloric Acid SCHEMBL1194812 | 0.69 | — | — | |
| Hydrochloric Acid SCHEMBL17451119 | 0.66 | GAA (0.33) | — | |
| Hydrochloric Acid SCHEMBL15612466 | 0.66 | — | — | |
| Hydrochloric Acid SCHEMBL2046729 | 0.66 | — | — | |
| Hydrochloric Acid SCHEMBL7620278 | 0.65 | — | — | |
| Hydrochloric Acid SCHEMBL2961475 | 0.64 | MAPT (0.36) | — | |
| SCHEMBL16834202 | 0.62 | ALDH1A1 (0.34) | — | |
| SCHEMBL289539 | 0.62 | TAS1R3 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1161460-A4 | POLYOLEFIN COMPOSITIONS HAVING ENHANCED ULTRAVIOLET AND OXIDATIVE RESISTANCE AND METHODS FOR THEIR PRODUCTION AND USE | ADVANCED POLYMER TECHNOLOGIES (US) | 2002-04-17 | — | — | EP | disclosed |
| EP-1161460-A1 | POLYOLEFIN COMPOSITIONS HAVING ENHANCED ULTRAVIOLET AND OXIDATIVE RESISTANCE AND METHODS FOR THEIR PRODUCTION AND USE | Advanced Polymer Technologies, Inc. (US) | 2001-12-12 | — | — | EP | disclosed |
| WO-2000046256-A1 | POLYOLEFIN COMPOSITIONS HAVING ENHANCED ULTRAVIOLET AND OXIDATIVE RESISTANCE AND METHODS FOR THEIR PRODUCTION AND USE | ADVANCED POLYMER TECHNOLOGIES, INC. (US) | 2000-08-10 | — | — | WO | disclosed |