Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INSR | P06213 | 1/20 | 0.56 |
| ▸ | IGF1R | P08069 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.55 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.55 |
| ▸ | CDK2 | P24941 | 1/20 | 0.55 |
| ▸ | CDK3 | Q00526 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | CLK2 | P49760 | 2/20 | 0.52 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30725947 | 0.80 | ALDH1A1 (0.69) | ALDH1A1CYP1A2CYP3A4CYP2C9HIF1A | |
| SCHEMBL1548213 | 0.80 | ALDH1A1 (0.69) | ALDH1A1CYP1A2CYP3A4CYP2C9HIF1A | |
| SCHEMBL7571372 | 0.78 | INSR (0.58) | INSRIGF1RALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL7571488 | 0.78 | HPGD (0.62) | INSRIGF1RALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL12956464 | 0.76 | HPGD (0.46) | INSRIGF1RALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL19555316 | 0.76 | PTPN7 (0.55) | INSRIGF1RHSD17B10MAPTKDM4E | |
| SCHEMBL30025182 | 0.76 | PTPN7 (0.55) | INSRIGF1RHSD17B10MAPTKDM4E | |
| SCHEMBL27587625 | 0.76 | ALDH1A1 (0.58) | INSRIGF1RALDH1A1CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL7368705 | 0.75 | RAB9A (0.78) | ALDH1A1CYP1A2CYP3A4CYP2C9HIF1A | |
| SCHEMBL28573140 | 0.75 | KDM4E (0.71) | ALDH1A1CYP1A2CYP3A4CYP2C9HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0904769-B1 | Keratin fibre dye compositions containing Indazole amine derivatives and dyeing method | OREAL (FR) | 2002-09-25 | — | — | EP | claimed |
| US-6027538-A | OXIDATION DYEING OF KERATINOUS FIBERS CONTAINING AT LEAST ONE COUPLER SELECTED FROM INDAZOLEAMINE DERIVATIVES AND AT LEAST ONE OXIDATION BASE; POWERFUL, NOT VERY SELECTIVE HAIR DYES WHICH ARE CAPABLE OF GENERATING INTENSE COLOR | L'OREAL S.A. (FR) | 2000-02-22 | — | — | US | disclosed |