SCHEMBL30725947

SCHEMBL30725947

O=C(O)Nc1ccc2cn[nH]c2c1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.69
CYP1A2 P05177 2/20 0.69
CYP3A4 P08684 2/20 0.69
CYP2D6 P10635 2/20 0.69
CYP2C9 P11712 2/20 0.69
HIF1A Q16665 2/20 0.69
HSD17B10 Q99714 2/20 0.69
CYP2C19 P33261 1/20 0.69
PHLPP2 Q6ZVD8 1/20 0.69
KDM4E B2RXH2 8/20 0.64
MAPT P10636 7/20 0.64
RAB9A P51151 3/20 0.64
GAA P10253 2/20 0.64
CLK2 P49760 2/20 0.63
CLK4 Q9HAZ1 2/20 0.63
MAP4K4 O95819 1/20 0.63
DYRK1A Q13627 1/20 0.63
SRPK1 Q96SB4 1/20 0.63
HPGD P15428 3/20 0.62
NPC1 O15118 2/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1548213 1.00 ALDH1A1 (0.69) ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL1163706 0.87 ROCK2 (0.74) ALDH1A1MAPTRAB9ACLK2CLK4
SCHEMBL8774349 0.85 ALDH1A1 (0.67) ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL30026503 0.85 ALDH1A1 (0.67) ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL14045319 0.85 ROCK2 (0.77) ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL21688513 0.84 ROCK1 (0.79) ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL29429758 0.83 RAB9A (0.80) ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL3378320 0.83 RAB9A (0.80) ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C9
Hydrochloric Acid SCHEMBL7368705 0.82 RAB9A (0.78) ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL28573140 0.82 KDM4E (0.71) ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111491925-B Pesticidal compounds 巴斯夫欧洲公司 2023-12-29 CN disclosed