Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.52 |
| ▸ | CCR9 | P51686 | 4/20 | 0.49 |
| ▸ | STAT3 | P40763 | 1/20 | 0.48 |
| ▸ | KIF11 | P52732 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7595506 | 0.89 | FFAR4 (0.57) | FFAR4CCR9KEAP1NFE2L2 | |
| SCHEMBL28570098 | 0.84 | KIF11 (0.62) | FFAR4KIF11GSK3B | |
| SCHEMBL7566650 | 0.83 | ACLY (0.57) | FFAR4GSK3B | |
| SCHEMBL7573002 | 0.81 | ACLY (0.59) | GSK3B | |
| SCHEMBL26537255 | 0.81 | FFAR4 (0.57) | FFAR4CCR9KEAP1NFE2L2 | |
| SCHEMBL7577285 | 0.80 | FFAR4 (0.59) | FFAR4CCR9KEAP1NFE2L2 | |
| SCHEMBL7570513 | 0.79 | FFAR4 (0.64) | FFAR4KIF11GSK3B | |
| SCHEMBL26530288 | 0.79 | FFAR4 (0.54) | FFAR4CCR9STAT3 | |
| SCHEMBL7569763 | 0.78 | FFAR4 (0.59) | FFAR4CCR9 | |
| SCHEMBL7590053 | 0.78 | FFAR4 (0.59) | FFAR4CCR9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002083629-A1 | BISSULFONAMIDE DERIVATIVES AS INHIBITORS OF DEHYDROQUINATE SYNTHETASES AND TYPE II DEHYDROQUINASES | ARROW THERAPEUTICS LIMITED (GB) | 2002-10-24 | — | — | WO | disclosed |