Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 11/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7397206 | 0.88 | TACR3 (0.45) | SMN1; SMN2MAPK1ALDH1A1RAB9ANPC1 | |
| SCHEMBL7398285 | 0.80 | SMN1; SMN2 (0.42) | SMN1; SMN2MAPK1ALDH1A1RAB9ANPC1 | |
| SCHEMBL7398443 | 0.78 | CDK5 (0.43) | — | |
| SCHEMBL2559636 | 0.78 | RAB9A (0.64) | SMN1; SMN2MAPK1ALDH1A1RAB9ANPC1 | |
| SCHEMBL1169212 | 0.77 | CHEK1 (0.58) | SMN1; SMN2MAPK1ALDH1A1RAB9ANPC1 | |
| SCHEMBL4703916 | 0.76 | CTSB (0.54) | MAPK1ALDH1A1MAPTTP53HSD17B10 | |
| SCHEMBL2558958 | 0.76 | SMN1; SMN2 (0.74) | SMN1; SMN2RAB9ANPC1MEN1KMT2A | |
| Bromide SCHEMBL1146428 | 0.76 | CHEK1 (0.57) | SMN1; SMN2MAPK1ALDH1A1RAB9ANPC1 | |
| SCHEMBL15096777 | 0.74 | RAB9A (0.54) | SMN1; SMN2MAPK1ALDH1A1RAB9ANPC1 | |
| SCHEMBL14183837 | 0.73 | SMN1; SMN2 (0.72) | SMN1; SMN2MAPK1ALDH1A1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020156063-A1 | Arylacetamido-ketobenzoxazole as cysteine protease inhibitors | AXYS PHARMACEUTICALS, INC. | 2002-10-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020156063-A1 | Arylacetamido-ketobenzoxazole as cysteine protease inhibitors | SERPINB1, SPINT2, PRSS1 | SMN1; SMN2 4367/4885MAPK1 2161/4885ALDH1A1 347/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.