Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.66 |
| ▸ | PKM | P14618 | 2/20 | 0.63 |
| ▸ | POLB | P06746 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 5/20 | 0.61 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | PLAU | P00749 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7540532 | 0.89 | ALDH3A1 (0.62) | ALDH1A1PKMPOLBLMNAALDH3A1 | |
| SCHEMBL6680721 | 0.86 | ALDH3A1 (0.58) | ALDH1A1PKMPOLBLMNAALDH3A1 | |
| SCHEMBL6676324 | 0.86 | ALDH1A1 (0.58) | ALDH1A1PKMPOLBLMNAALDH3A1 | |
| SCHEMBL6677229 | 0.86 | VCAM1 (0.60) | ALDH1A1PKMPOLBLMNAALDH3A1 | |
| SCHEMBL96167 | 0.85 | ALDH1A1 (0.70) | ALDH1A1PKMPOLBLMNASMN1; SMN2 | |
| SCHEMBL5227535 | 0.84 | ALDH1A1 (0.69) | ALDH1A1PKMPOLBLMNASMN1; SMN2 | |
| SCHEMBL6680004 | 0.84 | ALDH1A1 (0.58) | ALDH1A1POLBLMNAALDH3A1SMN1; SMN2 | |
| SCHEMBL7536287 | 0.84 | ALDH3A1 (0.65) | ALDH1A1POLBLMNAALDH3A1SMN1; SMN2 | |
| SCHEMBL7580299 | 0.83 | ALDH1A1 (0.68) | ALDH1A1PKMPOLBLMNASMN1; SMN2 | |
| SCHEMBL7573014 | 0.83 | ALDH1A1 (0.68) | ALDH1A1PKMPOLBLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |