SCHEMBL7573192

SCHEMBL7573192

CS(=O)(=O)c1ccc(C(=O)O)c(Cl)c1O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.45
TSHR P16473 3/20 0.40
SELL P14151 1/20 0.38
SELP P16109 1/20 0.38
ACLY P53396 1/20 0.38
ALDH1A1 P00352 4/20 0.37
HSD17B10 Q99714 3/20 0.37
KDM4E B2RXH2 2/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
RXFP1 Q9HBX9 1/20 0.37
CYP1A2 P05177 3/20 0.36
HPGD P15428 3/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
MAPT P10636 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
ATM Q13315 1/20 0.36
GLO1 Q04760 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7807426 0.85 LMNA (0.47) LMNATSHRALDH1A1MEN1KMT2A
SCHEMBL3254341 0.83 HPGD (0.50) LMNATSHRSELLSELPACLY
SCHEMBL4032987 0.82 LMNA (0.45) LMNATSHRACLYALDH1A1HSD17B10
SCHEMBL9640727 0.82 LMNA (0.45) LMNATSHRALDH1A1HSD17B10KDM4E
SCHEMBL7627991 0.81 MITF (0.43) LMNATSHRALDH1A1HSD17B10KDM4E
Hydrochloric Acid SCHEMBL9649707 0.81 LMNA (0.44) LMNATSHRACLYALDH1A1HSD17B10
SCHEMBL29182539 0.81 LMNA (0.44) LMNATSHRSELLSELPACLY
SCHEMBL1778291 0.81 LMNA (0.44) LMNATSHRACLYALDH1A1CYP1A2
SCHEMBL1358700 0.80 ALDH1A1 (0.40) LMNASELLSELPALDH1A1HSD17B10
SCHEMBL31544300 0.80 TSHR (0.55) LMNATSHRACLYALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6448201-B1 FOR THE SELECTIVE CONTROL OF BROAD-LEAVED WEEDS AND GRASS WEEDS IN CROPS OF USEFUL PLANTS AVENTIS CROPSCIENCE GMBH (DE) 2002-09-10 US disclosed
EP-1235816-A1 BENZOYLCYCLOHEXANDIONE AND BENZOYLPYRAZOLS, METHOD FOR THE PRODUCTION AND USE THEREOF AS HERBICIDES AND PLANT GROWTH REGULATORS Bayer CropScience GmbH (DE) 2002-09-04 EP disclosed
WO-2001032636-A1 BENZOYLCYCLOHEXANDIONE AND BENZOYLPYRAZOLS, METHOD FOR THE PRODUCTION AND USE THEREOF AS HERBICIDES AND PLANT GROWTH REGULATORS AVENTIS CROPSCIENCE GMBH (DE) 2001-05-10 WO disclosed
US-6153759-A HERBICIDE COMPRISING A 5-MEMBERED OR 6-MEMBERED HETEROCYCLIC, SATURATED OR UNSATURATED RADICAL CONTAINING ONE TO THREE HETERO ATOMS SELECTED FROM THE GROUP CONSISTING OF OXYGEN, SULFUR AND NITROGEN BASF AKTIENGESELLSCHAFT (DE) 2000-11-28 US disclosed
EP-0810998-B1 PHENYL DIKETONE DERIVATIVES AS HERBICIDES BASF AG (DE) 2000-04-26 EP disclosed
EP-0810999-B1 ISOXAZOLYL-BENZOYL DERIVATIVES BASF AG (DE) 2000-01-12 EP disclosed
US-6004903-A 2-Anylocyclohexanediones having improved herbicidal properties BASF AKTIENGESELLSCHAFT (DE) 1999-12-21 US disclosed
EP-0811005-B1 HERBICIDAL BENZOYL DERIVATIVES BASF AG (DE) 1999-09-29 EP disclosed
US-5846907-A Herbicidally active pyrazol-4-ylbenzoyl compounds BASF AKTIENGESELLSCHAFT (DE) 1998-12-08 US disclosed
US-5846906-A Herbicidally active phenyldiketone compounds BASF AKTIENGESELLSCHAFT (DE) 1998-12-08 US disclosed
US-5834402-A HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1998-11-10 US disclosed
WO-1996026192-A1 ISOXAZOLYL-BENZOYL DERIVATIVES BASF AKTIENGESELLSCHAFT (DE) 1996-08-29 WO disclosed
WO-1996026200-A1 HERBICIDAL BENZOYL DERIVATIVES BASF AKTIENGESELLSCHAFT (DE) 1996-08-29 WO disclosed
US-RE34779-E Selective weed control at low dosage without adversely affecting crops NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1994-11-08 US disclosed
EP-0352543-B1 Pyrazole derivatives and herbicides containing them NISSAN CHEMICAL IND LTD (JP) 1994-09-28 EP disclosed
US-4986845-A PRE-AND POSTEMERGENCE NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1991-01-22 US disclosed
EP-0352543-A1 Pyrazole derivatives and herbicides containing them NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1990-01-31 EP disclosed