Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLCN2 | P51788 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | XDH | P47989 | 1/20 | 0.46 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16862346 | 0.85 | KMT2A (0.56) | RAB9AALDH1A1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL10144156 | 0.82 | FABP4 (0.65) | CLCN2RAB9AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL8285642 | 0.80 | CXCR2 (0.60) | CLCN2ALDH1A1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL28276373 | 0.78 | POLB (0.48) | ALDH1A1KMT2ACXCR2MEN1HPGD | |
| SCHEMBL2445505 | 0.77 | CXCR2 (0.46) | CLCN2RAB9AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL7566561 | 0.77 | RAB9A (0.62) | RAB9AALDH1A1NPC1SMN1; SMN2MAPT | |
| SCHEMBL7568727 | 0.77 | AKR1C3 (0.54) | XDHSLC22A12MAPTKMT2ACXCR2 | |
| SCHEMBL7829395 | 0.75 | ALDH1A1 (0.70) | RAB9AALDH1A1NPC1SMN1; SMN2MAPT | |
| SCHEMBL6476627 | 0.75 | MEN1 (0.63) | CLCN2RAB9AALDH1A1NPC1MAPT | |
| Phthalic Acid SCHEMBL28190444 | 0.74 | ALDH1A1 (0.64) | CLCN2ALDH1A1SMN1; SMN2KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934278-B1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LTD (GB) | 2002-09-04 | — | — | EP | disclosed |
| US-6114332-A | BACTERICIDES | XENOVA LIMITED (GB) | 2000-09-05 | — | — | US | disclosed |
| EP-0934278-A1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LIMITED (GB) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998017650-A1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LIMITED (GB) | 1998-04-30 | — | — | WO | disclosed |