Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 16/20 | 0.62 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.47 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7571685 | 0.88 | TACR1 (0.57) | TACR1 | |
| SCHEMBL6926561 | 0.81 | TACR1 (0.65) | TACR1TBXAS1 | |
| SCHEMBL7572338 | 0.78 | TACR1 (1.00) | TACR1 | |
| SCHEMBL8660161 | 0.73 | TBXAS1 (0.50) | TACR1TBXAS1GPR17 | |
| Hydrochloric Acid SCHEMBL7790354 | 0.72 | TACR1 (0.64) | TACR1TBXAS1 | |
| SCHEMBL7572603 | 0.71 | MAP2 (0.46) | TACR1GPR17 | |
| SCHEMBL6928199 | 0.71 | TACR1 (0.65) | TACR1TBXAS1 | |
| SCHEMBL7658708 | 0.69 | TACR1 (0.58) | TACR1TBXAS1 | |
| SCHEMBL4831256 | 0.69 | ALDH1A1 (0.46) | — | |
| SCHEMBL7790361 | 0.68 | TACR1 (0.61) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020022624-A1 | Azaindole derivatives and their use as therapeutic agents | MERCK SHARP & DOHME LTD. (GB) | 2002-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020022624-A1 | Azaindole derivatives and their use as therapeutic agents | HTR2B, HNMT, HTR1B | TACR1 1385/4885TBXAS1 787/4885GPR17 409/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.