SCHEMBL757386

SCHEMBL757386

Cc1cc(-c2c(C)ccc(O)c2-c2cc(C)c(O)cc2C)c(C)cc1O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.54
ALOX15 P16050 2/20 0.54
HSD17B10 Q99714 2/20 0.54
CYP1A2 P05177 2/20 0.54
KDM4E B2RXH2 1/20 0.54
CYP3A4 P08684 1/20 0.54
CYP2D6 P10635 1/20 0.54
MAPT P10636 1/20 0.54
G6PD P11413 1/20 0.54
CYP2C9 P11712 1/20 0.54
PKM P14618 1/20 0.54
HPGD P15428 1/20 0.54
ALOX12 P18054 1/20 0.54
MAPK1 P28482 1/20 0.54
CYP2C19 P33261 1/20 0.54
CCR6 P51684 1/20 0.54
HIF1A Q16665 1/20 0.54
NPSR1 Q6W5P4 1/20 0.54
TSHR P16473 1/20 0.43
CASP1 P29466 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8894430 0.80 KDM4E (0.50) ALDH1A1ALOX15HSD17B10CYP1A2KDM4E
SCHEMBL17557774 0.78 ALDH1A1 (0.44) ALDH1A1ALOX15HSD17B10CYP1A2KDM4E
SCHEMBL4388616 0.77 KDM4E (0.68) ALDH1A1ALOX15HSD17B10CYP1A2KDM4E
SCHEMBL30693660 0.77 KDM4E (0.68) ALDH1A1ALOX15HSD17B10CYP1A2KDM4E
SCHEMBL4950434 0.76 KDM4E (0.50) ALDH1A1ALOX15HSD17B10CYP1A2KDM4E
SCHEMBL31545845 0.75 ALDH1A1 (0.75) ALDH1A1ALOX15HSD17B10CYP1A2KDM4E
Ethane SCHEMBL28289826 0.75 KDM4E (0.48) ALDH1A1ALOX15HSD17B10CYP1A2KDM4E
SCHEMBL4363656 0.74 ALDH1A1 (0.52) ALDH1A1ALOX15HSD17B10CYP1A2KDM4E
SCHEMBL3787886 0.73 NUDT1 (0.44) ALDH1A1ALOX15HSD17B10CYP1A2KDM4E
SCHEMBL15511832 0.72 KDM4E (0.56) ALDH1A1ALOX15HSD17B10CYP1A2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10577449-B2 Phenolic-hydroxyl-group-containing novolac resin and resist film DIC CORPORATION (JP) 2020-03-03 US disclosed
US-10162260-B2 Photosensitive resin composition, protective film, and liquid crystal display element CHI MEI CORPORATION (TW) 2018-12-25 US disclosed
US-10067422-B2 Photosensitive resin composition for forming interlayer insulating film, interlayer insulating film, and method for forming interlayer insulating film TOKYO OHKA KOGYO CO. LTD. (JP) 2018-09-04 US disclosed
US-9975830-B2 Compound containing modified phenolic hydroxy group, method for producing compound containing modified phenolic hydroxy group, photosensitive composition, resist material, and resist coating film DIC CORPORATION (JP) 2018-05-22 US disclosed
US-20180134834-A1 PHENOLIC-HYDROXYL-GROUP-CONTAINING NOVOLAC RESIN AND RESIST FILM DIC CORPORATION (JP) 2018-05-17 US disclosed
US-9963536-B2 Phenolic hydroxyl group-containing resin, production method therefor, photosensitive composition, resist material, coating film, curable composition and cured product thereof, and resist underlayer film DIC CORPORATION (JP) 2018-05-08 US disclosed
US-9851638-B2 Photosensitive polysiloxane composition and uses thereof CHI MEI CORPORATION (TW) 2017-12-26 US disclosed
US-9765175-B2 Modified hydroxy naphthalene novolak resin, production method for modified hydroxy naphthalene novolak resin, photosensitive composition, resist material and coating DIC CORPORATION (JP) 2017-09-19 US disclosed
US-20170255099-A1 PHOTOSENSITIVE RESIN COMPOSITION FOR FORMING INTERLAYER INSULATING FILM, INTERLAYER INSULATING FILM, AND METHOD FOR FORMING INTERLAYER INSULATING FILM TOKYO OHKA KOGYO CO., LTD. (JP) 2017-09-07 US disclosed
US-20170168390-A1 PHOTOSENSITIVE RESIN COMPOSITION, PROTECTIVE FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT CHI MEI CORPORATION (TW) 2017-06-15 US disclosed
EP-1469353-A1 TWO-LAYER FILM AND METHOD OF FORMING PATTERN WITH THE SAME JSR Corporation (JP) 2004-10-20 EP disclosed
US-20040131963-A1 Two-layer film and method of forming pattern with the same JSR CORPORATION (JP) 2004-07-08 US disclosed
US-5677102-A DISSOLVING AN ALKALI SOLUBLE RESIN AND A QUINONEDIAZIDE GROUP CONTAINING COMPOUND; HEATING TOKYO OHKA KOGYO CO., LTD. (JP) 1997-10-14 US disclosed
US-5604077-A MIXTURE OF ALKALI-SOLUBLE NOVOLAK AND A QUINONE DIAZIDE PHOTOSENSITIZER; HEAT RESISTANCE, RESOLUTION, ANTIFOULING AGENTS TOKYO OHKA KOGYO CO., LTD. (JP) 1997-02-18 US disclosed
US-5601961-A QUINONE DIAZIDE GROUP-CONTAINING COMPOUND AS PHOTOSENSITIZING AGENT, ALKALI-SOLUBLE RESINOUS INGREDIENT AS FILM-FORMING AGENT MADE FROM A BLEND OF AT LEAST TWO NOVOLAK-TYPE RESINS FROM M-AND P-CRESOL, A XYLENOL AND A TRIMETHYLPHENOL TOKYO OHKA KOGYO CO., LTD. (JP) 1997-02-11 US disclosed
US-5576138-A MIXTURE OF RESIN, PHOTOSENSITIZER AND BENZOPHENONE COMPOUND TOKYO OHKA KOGYO CO., LTD. (JP) 1996-11-19 US disclosed
US-5501936-A IMPROVED RESOLUTION OF VERY FINE PATTERNS TOKYO OHKA KOGYO CO., LTD. (JP) 1996-03-26 US disclosed
US-5478692-A Fine patterning for electronics TOKYO OHKA KOGYO CO., LTD. (JP) 1995-12-26 US disclosed
US-5434031-A Positive-working naphthoquinone diazide photoresist composition containing specific hydroxy compound additive TOKYO OHKA KOGYO CO., LTD. (JP) 1995-07-18 US disclosed
US-5332647-A Photosensitive resins for elements TOKYO OHKA KOGYO CO., LTD. (JP) 1994-07-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180134834-A1 PHENOLIC-HYDROXYL-GROUP-CONTAINING NOVOLAC RESIN AND RESIST FILM HACL2, ASH2L, HEATR1 ALDH1A1 67/4885ALOX15 613/4885HSD17B10 68/4885
US-10577449-B2 Phenolic-hydroxyl-group-containing novolac resin and resist film HACL2, ASH2L, HEATR1 ALDH1A1 67/4885ALOX15 613/4885HSD17B10 68/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.