Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.62 |
| ▸ | CA2 | P00918 | 1/20 | 0.62 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.60 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.60 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.57 |
| ▸ | ESR1 | P03372 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7572279 | 0.86 | FFAR4 (0.73) | CA1CA2FFAR4ALDH1A1MEN1 | |
| SCHEMBL7501950 | 0.85 | CA1 (0.81) | CA1CA2HSD17B3HSD17B2FFAR4 | |
| SCHEMBL29561406 | 0.83 | MEN1 (0.59) | HSD17B3HSD17B2FFAR4ALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL5797806 | 0.83 | CA1 (0.79) | CA1CA2HSD17B3HSD17B2FFAR4 | |
| SCHEMBL1891805 | 0.81 | ALDH1A1 (0.72) | CA1CA2HSD17B3HSD17B2FFAR4 | |
| SCHEMBL3366221 | 0.80 | CES1 (0.81) | CA1CA2HSD17B3HSD17B2FFAR4 | |
| SCHEMBL7595616 | 0.80 | KMT2A (0.51) | CA1CA2FFAR4ALDH1A1MEN1 | |
| SCHEMBL7594942 | 0.79 | KEAP1 (0.62) | CA1CA2FFAR4MEN1KMT2A | |
| SCHEMBL29561923 | 0.79 | CA1 (0.63) | CA1CA2HSD17B3HSD17B2FFAR4 | |
| SCHEMBL15068209 | 0.78 | CA1 (0.61) | CA1CA2HSD17B3HSD17B2FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |