Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.73 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | PKM | P14618 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.60 |
| ▸ | IL1RN | P18510 | 1/20 | 0.60 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.60 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | GFER | P55789 | 1/20 | 0.57 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.57 |
| ▸ | HTR6 | P50406 | 3/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7574073 | 0.86 | CA1 (0.62) | FFAR4LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL14115705 | 0.85 | FFAR4 (0.77) | FFAR4LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL5800778 | 0.85 | FFAR4 (0.68) | FFAR4LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL3930917 | 0.85 | FFAR4 (0.68) | FFAR4LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL14086768 | 0.82 | FFAR4 (0.60) | FFAR4LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL3717185 | 0.82 | FABP4 (0.63) | FFAR4LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL3409664 | 0.81 | HTR6 (0.66) | FFAR4LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL810795 | 0.80 | KMT2A (0.91) | LMNASMN1; SMN2MEN1KMT2APKM | |
| SCHEMBL29561406 | 0.80 | MEN1 (0.59) | FFAR4LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL4968417 | 0.80 | FFAR4 (0.71) | FFAR4LMNASMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |