SCHEMBL7574422

SCHEMBL7574422

C=CCC(=Cc1ccccc1)c1cccc(O)c1O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FNTA P49354 1/20 0.36
FNTB P49356 1/20 0.36
MAPT P10636 3/20 0.36
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
BCHE P06276 1/20 0.36
CYP2C19 P33261 1/20 0.36
MTNR1A P48039 2/20 0.36
MTNR1B P49286 2/20 0.36
ALOX5 P09917 1/20 0.35
TERT O14746 1/20 0.35
RAB9A P51151 2/20 0.35
TDP1 Q9NUW8 2/20 0.35
KDM4E B2RXH2 1/20 0.35
KCNH2 Q12809 1/20 0.35
NPC1 O15118 1/20 0.35
ATM Q13315 1/20 0.34
ADAMTS4 O75173 1/20 0.34
ALDH1A1 P00352 1/20 0.34
EGFR P00533 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22411162 0.90 MAPT (0.41) MAPTMEN1KMT2ABCHECYP2C19
SCHEMBL10339712 0.86 MEN1 (0.42) MEN1KMT2AMTNR1AMTNR1BALDH1A1
SCHEMBL9114636 0.83 ESR1 (0.47) MAPTMEN1KMT2ABCHECYP2C19
SCHEMBL7756538 0.79 MTNR1A (0.49) MEN1KMT2AMTNR1AMTNR1BALDH1A1
SCHEMBL7603630 0.79 MTNR1A (0.49) MEN1KMT2AMTNR1AMTNR1BALDH1A1
SCHEMBL9284800 0.79 MTNR1A (0.45) MEN1KMT2AMTNR1AMTNR1BALDH1A1
SCHEMBL7603627 0.79 MTNR1A (0.49) MEN1KMT2AMTNR1AMTNR1BALDH1A1
SCHEMBL9243599 0.78 ALDH1A1 (0.38) MAPTMEN1KMT2AMTNR1AMTNR1B
SCHEMBL7574403 0.73 BCHE (0.41) MAPTMEN1KMT2ABCHERAB9A
SCHEMBL7059289 0.73 ALDH1A1 (0.41) FNTAFNTBMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5873981-A Recovery of anhydrous acids THE DOW CHEMICAL COMPANY (US) 1999-02-23 US claimed
EP-0927148-A3 PREPARATION OF 4,4'-DIHYDROXY-ALPHA-ALKYLSTILBENE WITH REDUCED DIMER FORMATION MICHIGAN MOLECULAR INSTITUTE (US) 2002-11-20 EP disclosed
WO-1998011042-A3 PREPARATION OF 4,4'-DIHYDROXY-ALPHA-ALKYLSTILBENE WITH REDUCED DIMER FORMATION DOW CHEMICAL CO (US) 2002-10-03 WO disclosed
EP-0927148-B1 PREPARATION OF 4,4'-DIHYDROXY-ALPHA-ALKYLSTILBENE WITH REDUCED DIMER FORMATION MICHIGAN MOLECULAR INST (US) 2001-03-07 EP disclosed
EP-0949996-A2 LAMINATE STRUCTURES FOR FUEL CONTAINERS THE DOW CHEMICAL COMPANY (US) 1999-10-20 EP disclosed
EP-0948479-A1 RECOVERY OF ANHYDROUS ALKANESULPHONIC ACIDS THE DOW CHEMICAL COMPANY (US) 1999-10-13 EP disclosed
EP-0948479-A1 RECOVERY OF ANHYDROUS ALKANESULPHONIC ACIDS THE DOW CHEMICAL COMPANY (US) 1999-10-13 EP disclosed
EP-0927148-A2 PREPARATION OF 4,4'-DIHYDROXY-ALPHA-ALKYLSTILBENE WITH REDUCED DIMER FORMATION THE DOW CHEMICAL COMPANY (US) 1999-07-07 EP disclosed
US-5873981-A Recovery of anhydrous acids THE DOW CHEMICAL COMPANY (US) 1999-02-23 US disclosed
US-5873981-A Recovery of anhydrous acids THE DOW CHEMICAL COMPANY (US) 1999-02-23 US disclosed
WO-1998011042-A2 PREPARATION OF 4,4'-DIHYDROXY-ALPHA-ALKYLSTILBENE WITH REDUCED DIMER FORMATION THE DOW CHEMICAL COMPANY (US) 1998-03-19 WO disclosed
US-5723692-A Preparation of 4,4'-dihydroxy-'alkylstiblbene with reduced dimer formation THE DOW CHEMICAL COMPANY (US) 1998-03-03 US disclosed
US-5723692-A Preparation of 4,4'-dihydroxy-'alkylstiblbene with reduced dimer formation THE DOW CHEMICAL COMPANY (US) 1998-03-03 US disclosed
US-5475155-A Reacting an alpha-haloketone with a phenolic-hydroxyl containing compound and a strong protonic acid; neutralization; dehydrohalogenation; dealkylation THE DOW CHEMICAL COMPANY (US) 1995-12-12 US disclosed
WO-1995015301-A1 PREPARATION OF 4,4'-DIHYDROXY-ALPHA-ALKYLSTILBENES AND 4,4'-DIHYDROXY-ALPHA, ALPHA'-DIALKYLSTILBENES THE DOW CHEMICAL COMPANY (US) 1995-06-08 WO disclosed
US-5414125-A Epoxy resin curing agent THE DOW CHEMICAL COMPANY (US) 1995-05-09 US disclosed
EP-0579743-A1 DIAMINO-ALPHA-ALKYLSTILBENES THE DOW CHEMICAL COMPANY (US) 1994-01-26 EP disclosed
US-5268434-A Curable composition THE DOW CHEMICAL COMPANY (US) 1993-12-07 US disclosed
US-5264502-A Curable resins for rod like structure for liquid crystals THE DOW CHEMICAL COMPANY (US) 1993-11-23 US disclosed
WO-1992018460-A1 DIAMINO-ALPHA-ALKYLSTILBENES THE DOW CHEMICAL COMPANY (US) 1992-10-29 WO disclosed