Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7574542 | 1.00 | NFE2L2 (0.47) | NFE2L2RELAMAPTMEN1KMT2A | |
| SCHEMBL7574920 | 0.85 | ALDH1A1 (0.40) | MAPTMEN1KMT2AL3MBTL1LMNA | |
| SCHEMBL7574921 | 0.85 | ALDH1A1 (0.40) | MAPTMEN1KMT2AL3MBTL1LMNA | |
| SCHEMBL7580944 | 0.85 | MAPT (0.43) | MAPTMEN1KMT2ATDP1LMNA | |
| SCHEMBL7580939 | 0.85 | MAPT (0.43) | MAPTMEN1KMT2ATDP1LMNA | |
| SCHEMBL7571646 | 0.84 | GRIN1 (0.39) | MAPTMEN1KMT2ALMNAHPGD | |
| SCHEMBL7571650 | 0.84 | GRIN1 (0.39) | MAPTMEN1KMT2ALMNAHPGD | |
| SCHEMBL7579599 | 0.81 | TRPA1 (0.45) | MAPTMEN1KMT2AL3MBTL1HTT | |
| SCHEMBL7579606 | 0.81 | TRPA1 (0.45) | MAPTMEN1KMT2AL3MBTL1HTT | |
| SCHEMBL7573370 | 0.80 | MAPT (0.35) | MAPTMEN1KMT2AL3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0810199-B1 | Method for producing propargylamine compounds | SUMITOMO CHEMICAL CO (JP) | 2002-09-25 | — | — | EP | disclosed |
| US-5756769-A | Method for producing propargylamine compounds | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 1998-05-26 | — | — | US | disclosed |
| EP-0810199-A1 | Method for producing propargylamine compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-12-03 | — | — | EP | disclosed |