Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | LMNA | P02545 | 4/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.52 |
| ▸ | TTR | P02766 | 1/20 | 0.52 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | PGR | P06401 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
| ▸ | AR | P10275 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6244215 | 0.85 | KCNQ2 (0.53) | ALDH1A1MAPTLMNAPKMHTT | |
| SCHEMBL3176692 | 0.84 | MEN1 (0.50) | ALDH1A1MAPTLMNAPKMHTT | |
| SCHEMBL7578887 | 0.84 | LMNA (0.50) | ALDH1A1MAPTLMNAPKMHTT | |
| SCHEMBL7574624 | 0.82 | ALDH1A1 (0.42) | ALDH1A1MAPTLMNAPKMHTT | |
| SCHEMBL360635 | 0.79 | CXCL8 (0.45) | ALDH1A1LMNAMEN1MT-CO2TTR | |
| SCHEMBL2483409 | 0.79 | RAB9A (0.48) | ALDH1A1HTTHPGDCYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL1695958 | 0.78 | RAB9A (0.47) | ALDH1A1MAPTLMNAHTTHPGD | |
| SCHEMBL6809250 | 0.78 | CXCL8 (0.44) | ALDH1A1LMNAMEN1MT-CO2TTR | |
| SCHEMBL11271011 | 0.78 | CXCL8 (0.44) | ALDH1A1LMNAMEN1MT-CO2TTR | |
| SCHEMBL29709443 | 0.77 | CYP2C9 (0.42) | ALDH1A1MAPTLMNAPKMHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242069-A2 | ALBUMIN-BINDING COMPOUNDS THAT PREVENT NONENZYMATIC GLYCATION AND THAT MAY BE USED FOR TREATMENT OF GLYCATION-RELATED PATHOLOGIES | EXOCELL, INC. (US) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001003684-A2 | ALBUMIN-BINDING COMPOUNDS THAT PREVENT NONENZYMATIC GLYCATION AND THAT MAY BE USED FOR TREATMENT OF GLYCATION-RELATED PATHOLOGIES | EXOCELL, INC. (US) | 2001-01-18 | — | — | WO | disclosed |