Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | TDP2 | O95551 | 1/20 | 0.34 |
| ▸ | APAF1 | O14727 | 1/20 | 0.34 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7584565 | 0.89 | ALDH1A1 (0.41) | ALDH1A1GAASMN1; SMN2KDM4ETDP2 | |
| SCHEMBL7585605 | 0.78 | KDM4E (0.34) | ALDH1A1GAASMN1; SMN2KDM4ETDP2 | |
| SCHEMBL4864333 | 0.75 | TNF (0.36) | ALDH1A1GAAKDM4EMAPTTSHR | |
| SCHEMBL7576603 | 0.66 | ALDH1A1 (0.37) | ALDH1A1GAASMN1; SMN2KDM4ETDP2 | |
| SCHEMBL7513508 | 0.66 | ALDH1A1 (0.35) | ALDH1A1SMN1; SMN2KDM4EKCNH2MEN1 | |
| SCHEMBL2081998 | 0.65 | ADRB2 (0.45) | MAPTKCNH2MEN1KMT2AHPGD | |
| SCHEMBL7585608 | 0.64 | APAF1 (0.32) | SMN1; SMN2TDP2APAF1SMAD3MAPT | |
| SCHEMBL31522062 | 0.61 | MAPT (0.45) | ALDH1A1GAASMN1; SMN2KDM4ETDP2 | |
| SCHEMBL2898740 | 0.61 | TSHR (0.44) | ALDH1A1GAASMN1; SMN2KDM4EMAPT | |
| SCHEMBL7574847 | 0.59 | TDP2 (0.48) | ALDH1A1GAAKDM4ETDP2APAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020049223-A1 | Quinoline and naphthyridine carboxylic acid antibacterials | ABBOTT LABORATORIES | 2002-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020049223-A1 | Quinoline and naphthyridine carboxylic acid antibacterials | NQO2, NQO1, NDUFA7 | ALDH1A1 145/4885GAA 171/4885SMN1; SMN2 3221/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.