Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 12/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7568813 | 0.88 | HCAR3 (0.69) | HCAR3MAPTKMT2AMEN1CRHBP | |
| SCHEMBL7574965 | 0.78 | MAPT (0.51) | HCAR3MAPTKMT2AMEN1CRHBP | |
| SCHEMBL9192581 | 0.77 | MAPT (0.64) | HCAR3MAPTKMT2AMEN1CRHBP | |
| SCHEMBL6172138 | 0.77 | HCAR3 (0.70) | HCAR3MAPTKMT2AMEN1 | |
| Morpholine SCHEMBL28105354 | 0.76 | TSHR (0.71) | HCAR3MAPTKMT2AMEN1 | |
| SCHEMBL7572903 | 0.76 | MAPT (0.56) | HCAR3MAPTKMT2AMEN1CRHBP | |
| SCHEMBL9043092 | 0.76 | KMT2A (0.72) | HCAR3MAPTKMT2AMEN1CRHBP | |
| Morpholine SCHEMBL28035212 | 0.75 | PLA2G4B (0.53) | HCAR3MAPTKMT2AMEN1NPC1 | |
| Morpholine SCHEMBL28030087 | 0.75 | TSHR (0.69) | HCAR3MAPTKMT2AMEN1 | |
| SCHEMBL8396995 | 0.74 | NPC1 (0.72) | MAPTKMT2AMEN1CRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0685470-B1 | Benzene derivatives and pharmaceutical composition | KUREHA CHEMICAL IND CO LTD (JP) | 2002-09-11 | — | — | EP | disclosed |
| EP-0685470-A2 | Benzene derivatives and pharmaceutical composition | Kureha Chemical Industry Co., Ltd. (JP) | 1995-12-06 | — | — | EP | disclosed |