Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | CRHBP | P24387 | 2/20 | 0.64 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9043092 | 0.91 | KMT2A (0.72) | MAPTKMT2ACRHBPCRHR2MEN1 | |
| SCHEMBL9195505 | 0.90 | MAPT (0.55) | MAPTKMT2ACRHBPCRHR2MEN1 | |
| SCHEMBL7568813 | 0.88 | HCAR3 (0.69) | MAPTKMT2ACRHBPCRHR2MEN1 | |
| SCHEMBL8391902 | 0.84 | MAPT (0.78) | MAPTKMT2ACRHBPCRHR2MEN1 | |
| SCHEMBL7572903 | 0.83 | MAPT (0.56) | MAPTKMT2ACRHBPCRHR2MEN1 | |
| SCHEMBL7574965 | 0.82 | MAPT (0.51) | MAPTKMT2ACRHBPCRHR2MEN1 | |
| SCHEMBL12388226 | 0.82 | MAPT (0.56) | MAPTKMT2ACRHBPCRHR2MEN1 | |
| SCHEMBL8396995 | 0.82 | NPC1 (0.72) | MAPTKMT2ACRHBPCRHR2MEN1 | |
| SCHEMBL9192588 | 0.81 | HCAR3 (0.77) | MAPTKMT2ACRHBPCRHR2RAB9A | |
| SCHEMBL29086200 | 0.81 | KMT2A (0.62) | MAPTKMT2ACRHBPCRHR2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0425921-B1 | Benzimidazole derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-08-09 | — | — | EP | disclosed |
| US-5250554-A | Cardiovascular disorders | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-10-05 | — | — | US | disclosed |
| US-5128356-A | Angiotensin antagonist; cardiovascular disorders | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-07-07 | — | — | US | disclosed |
| EP-0425921-A1 | Benzimidazole derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-05-08 | — | — | EP | disclosed |