Sugi Predict

Sugi Predict / Compounds / Bifenox

Bifenox

Bifenox

SCHEMBL7575338

COC(=O)c1cc(Oc2ccc(Cl)cc2Cl)ccc1[N+](=O)[O-].Cc1ccc(NC(=O)N(C)C)cc1Cl

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 2/20 0.71
▸ PNLIP P16233 7/20 0.46
▸ LMNA P02545 2/20 0.46
▸ PPIA P62937 1/20 0.44
▸ KMT2A Q03164 4/20 0.43
▸ MEN1 O00255 3/20 0.43
▸ GAA P10253 1/20 0.43
▸ PKM P14618 1/20 0.43
▸ TTR P02766 1/20 0.43
▸ PPOX P50336 1/20 0.43
▸ PARG Q86W56 1/20 0.43
▸ MAPT P10636 4/20 0.43
▸ NPSR1 Q6W5P4 1/20 0.43
▸ STK39 Q9UEW8 1/20 0.43
▸ MAPK1 P28482 1/20 0.43
▸ L3MBTL1 Q9Y468 1/20 0.43
▸ ALDH1A1 P00352 1/20 0.42
▸ SMN1; SMN2 Q16637 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bifenox SCHEMBL7577683 0.88 TDP1 (0.71) TDP1PNLIPLMNAKMT2AMEN1
Bifenox SCHEMBL8541647 0.84 TDP1 (1.00) TDP1LMNAKMT2AMEN1GAA
Bifenox SCHEMBL38816 0.84 TDP1 (1.00) TDP1LMNAKMT2AMEN1GAA
Bifenox SCHEMBL30862569 0.84 TDP1 (1.00) TDP1LMNAKMT2AMEN1GAA
Bifenox SCHEMBL28419037 0.83 TDP1 (0.98) TDP1LMNAKMT2AMEN1GAA
Acifluorfen SCHEMBL7584678 0.82 TDP1 (0.70) TDP1PNLIPLMNAPPIAKMT2A
Bifenox SCHEMBL27552005 0.82 TDP1 (0.89) TDP1LMNAKMT2AMEN1GAA
SCHEMBL10785622 0.81 TDP1 (0.81) TDP1LMNAKMT2AMEN1TTR
Bifenox SCHEMBL7583476 0.81 TDP1 (0.74) TDP1PNLIPLMNAKMT2AMEN1
Dimefuron SCHEMBL7577966 0.81 KMT2A (0.60) TDP1PNLIPLMNAKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT TDP1 1969/4885PNLIP 1837/4885LMNA 3881/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.