Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.69 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.69 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.50 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28269439 | 0.84 | ALOX15 (0.51) | ALOX15PTGS2PIK3R1PIK3CAALDH1A1 | |
| SCHEMBL1772025 | 0.81 | ALOX15 (0.49) | ALOX15PTGS2PIK3R1PIK3CAALDH1A1 | |
| SCHEMBL13930825 | 0.80 | NPC1 (0.63) | ALOX15PTGS2ALDH1A1HPGDKDM4E | |
| SCHEMBL3263396 | 0.78 | CASP3 (0.65) | ALOX15PTGS2ALDH1A1HPGDKDM4E | |
| SCHEMBL1217073 | 0.78 | ALOX15 (0.57) | ALOX15PTGS2PIK3R1PIK3CAALDH1A1 | |
| SCHEMBL5000299 | 0.77 | PIK3R1 (0.47) | ALOX15PTGS2PIK3R1PIK3CAALDH1A1 | |
| SCHEMBL1477744 | 0.77 | ALDH1A1 (0.48) | ALOX15PTGS2PIK3R1PIK3CAALDH1A1 | |
| SCHEMBL29550402 | 0.77 | ALDH1A1 (0.48) | ALOX15PTGS2PIK3R1PIK3CAALDH1A1 | |
| SCHEMBL18519819 | 0.77 | ALDH1A1 (0.48) | ALOX15PTGS2PIK3R1PIK3CAALDH1A1 | |
| SCHEMBL5141631 | 0.76 | TTR (0.56) | ALOX15PTGS2ALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0773248-B1 | Polymers with heterocyclic side groups | MISSISSIPPI POLYMER TECHNOLOGI (US) | 2002-10-02 | — | — | EP | disclosed |
| US-5668245-A | PHENYLENE POLYMERS WITH HETEROCYCLIC SIDE GROUPS | MAXDEM INCORPORATED (US) | 1997-09-16 | — | — | US | disclosed |
| EP-0773248-A1 | Polymers with heterocyclic side groups | MAXDEM INCORPORATED (US) | 1997-05-14 | — | — | EP | disclosed |
| EP-0318214-B1 | Tri- and tetra-substituted-oxetanes and -tetrahydrofurans and intermediates thereof | SCHERING CORP (US) | 1994-12-14 | — | — | EP | disclosed |
| US-5039676-A | Fungicide, antiallergens | SCHERING CORPORATION (US) | 1991-08-13 | — | — | US | disclosed |
| EP-0386143-A1 | TRI- AND TETRA-SUBSTITUTED-OXETANES AND TETRAHYDROFURANS AND INTERMEDIATES THEREOF | SCHERING CORPORATION (US) | 1990-09-12 | — | — | EP | disclosed |
| WO-1989004829-A1 | TRI- AND TETRA-SUBSTITUTED-OXETANES AND TETRAHYDROFURANS AND INTERMEDIATES THEREOF | SCHERING CORPORATION (US) | 1989-06-01 | — | — | WO | disclosed |
| EP-0318214-A1 | Tri- and tetra-substituted-oxetanes and -tetrahydrofurans and intermediates thereof | SCHERING CORPORATION (US) | 1989-05-31 | — | — | EP | disclosed |