Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | ESR1 | P03372 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 8/20 | 0.53 |
| ▸ | NPC1 | O15118 | 7/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.53 |
| ▸ | TP53 | P04637 | 4/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 4/20 | 0.51 |
| ▸ | GRM5 | P41594 | 1/20 | 0.51 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | USP2 | O75604 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13930942 | 0.87 | CASP3 (0.63) | CASP3ALOX15PTGS2HSD17B10KDM4E | |
| SCHEMBL4252206 | 0.86 | CASP3 (0.55) | CASP3ALOX15PTGS2HSD17B10KDM4E | |
| SCHEMBL3266503 | 0.86 | CASP3 (0.62) | CASP3ALOX15PTGS2HSD17B10KDM4E | |
| SCHEMBL3261588 | 0.79 | CASP3 (1.00) | CASP3HSD17B10KDM4EMAPTESR1 | |
| SCHEMBL3264375 | 0.78 | CASP3 (0.55) | CASP3ALOX15PTGS2HSD17B10KDM4E | |
| SCHEMBL7575670 | 0.78 | ALOX15 (0.69) | CASP3ALOX15PTGS2HSD17B10KDM4E | |
| SCHEMBL1217073 | 0.77 | ALOX15 (0.57) | CASP3ALOX15PTGS2HSD17B10KDM4E | |
| SCHEMBL13930825 | 0.77 | NPC1 (0.63) | ALOX15PTGS2HSD17B10KDM4EMAPT | |
| SCHEMBL13930938 | 0.75 | RAB9A (0.58) | CASP3HSD17B10KDM4EMAPTESR1 | |
| SCHEMBL3261757 | 0.75 | ALOX15 (0.54) | CASP3ALOX15PTGS2KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10827753-B2 | Compositions and methods for controlling nematodes | MONSANTO TECHNOLOGY LLC (US) | 2020-11-10 | — | — | US | claimed |
| US-20190343120-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | MONSANTO TECHNOLOGY LLC (US) | 2019-11-14 | — | — | US | claimed |
| US-20190208785-A1 | Composition and Methods for Reducing Nematodes | MONSANTO TECHNOLOGY LLC (US) | 2019-07-11 | — | — | US | claimed |
| EP-2947080-B1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | MONSANTO TECHNOLOGY LLC (US) | 2017-10-25 | — | — | EP | claimed |
| WO-2017106715-A1 | COMPOSITION AND METHODS FOR REDUCING NEMATODES | MONSANTO TECHNOLOGY LLC (US) | 2017-06-22 | — | — | WO | claimed |
| US-9420788-B2 | Compositions and methods for controlling nematodes | MONSANTO TECHNOLOGY LLC (US) | 2016-08-23 | — | — | US | claimed |
| EP-2947080-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | Monsanto Technology LLC (US) | 2015-11-25 | — | — | EP | claimed |
| US-20150150258-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | MONSANTO TECHNOLOGY LLC (US) | 2015-06-04 | — | — | US | claimed |
| EP-2184989-B1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | MONSANTO TECHNOLOGY LLC (US) | 2015-05-06 | — | — | EP | claimed |
| CN-104054719-A | Compositions And Methods For Controlling Nematodes | MONSANTO TECHNOLOGY LLC | 2014-09-24 | — | — | CN | claimed |
| US-8435999-B2 | Compositions and methods for controlling nematodes | MONSANTO TECHNOLOGY LLC (US) | 2013-05-07 | — | — | US | claimed |
| US-10827753-B2 | Compositions and methods for controlling nematodes | MONSANTO TECHNOLOGY LLC (US) | 2020-11-10 | — | — | US | disclosed |
| US-20190343120-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | MONSANTO TECHNOLOGY LLC (US) | 2019-11-14 | — | — | US | disclosed |
| US-20190327967-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | MONSANTO TECHNOLOGY LLC (US) | 2019-10-31 | — | — | US | disclosed |
| US-10375958-B2 | Compositions and methods for controlling nematodes | MONSANTO TECHNOLOGY LLC (US) | 2019-08-13 | — | — | US | disclosed |
| US-20130296166-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | DIVERGENCE, INC. | 2013-11-07 | — | — | US | disclosed |
| US-8435999-B2 | Compositions and methods for controlling nematodes | MONSANTO TECHNOLOGY LLC (US) | 2013-05-07 | — | — | US | disclosed |
| EP-2184989-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | Divergence, Inc. (US) | 2010-05-19 | — | — | EP | disclosed |
| WO-2009023721-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | DIVERGENCE, INC. (US) | 2009-02-19 | — | — | WO | disclosed |
| US-20090048311-A1 | Compostions and Methods for Controlling Nematodes | MONSANTO TECHNOLOGY LLC | 2009-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10827753-B2 | Compositions and methods for controlling nematodes | NOP2, ATL3, CYCS | CASP3 477/4885ALOX15 550/4885PTGS2 1250/4885 |
| US-20130296166-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | ATL3, NOP2, PTMS | CASP3 654/4885ALOX15 589/4885PTGS2 1425/4885 |
| US-20190343120-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | NOP2, ATL3, CYCS | CASP3 477/4885ALOX15 550/4885PTGS2 1250/4885 |
| US-20150150258-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | NOP2, ATL3, CYCS | CASP3 477/4885ALOX15 550/4885PTGS2 1250/4885 |
| US-20090048311-A1 | Compostions and Methods for Controlling Nematodes | NOP2, MT-CO3, CLPX | CASP3 634/4885ALOX15 1349/4885PTGS2 1432/4885 |
| US-20190208785-A1 | Composition and Methods for Reducing Nematodes | RPL41, SPOUT1, MASTL | CASP3 1319/4885ALOX15 1229/4885PTGS2 3016/4885 |
| US-10375958-B2 | Compositions and methods for controlling nematodes | NOP2, ATL3, CYCS | CASP3 477/4885ALOX15 550/4885PTGS2 1250/4885 |
| US-20190327967-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | NOP2, ATL3, CYCS | CASP3 477/4885ALOX15 550/4885PTGS2 1250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.