Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 7/20 | 0.39 |
| ▸ | FNTB | P49356 | 7/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 7/20 | 0.36 |
| ▸ | PLA2G10 | O15496 | 6/20 | 0.36 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.36 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.35 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.35 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.35 |
| ▸ | PLA2G12B | Q9BX93 | 1/20 | 0.35 |
| ▸ | PLA2G12A | Q9BZM1 | 1/20 | 0.35 |
| ▸ | PLA2G2F | Q9BZM2 | 1/20 | 0.35 |
| ▸ | PLA2G3 | Q9NZ20 | 1/20 | 0.35 |
| ▸ | PLA2G2E | Q9NZK7 | 1/20 | 0.35 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7572010 | 0.89 | MYC (0.41) | FNTAFNTBKAT6AFFAR1FFAR4 | |
| SCHEMBL7577374 | 0.79 | BCAT2 (0.45) | PLA2G2APLA2G10SLC9A1PLA2G1BPLA2G5 | |
| SCHEMBL7890739 | 0.74 | ALDH1A1 (0.46) | SLC9A1LMNAHTT | |
| SCHEMBL7904826 | 0.72 | FNTA (0.42) | FNTAFNTBFFAR1FFAR4 | |
| SCHEMBL7905941 | 0.71 | FNTA (0.44) | FNTAFNTB | |
| SCHEMBL7904559 | 0.71 | MYC (0.43) | FNTAFNTBFFAR1FFAR4HTT | |
| SCHEMBL27427563 | 0.71 | HTR7 (0.44) | — | |
| SCHEMBL1788703 | 0.70 | BCAT2 (0.59) | LMNAHTT | |
| SCHEMBL25238582 | 0.70 | CYP3A4 (0.38) | KAT6A | |
| SCHEMBL7904816 | 0.70 | FFAR1 (0.42) | FNTAFNTBFFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020019527-A1 | Substituted phenyl farnesyltransferase inhibitors | ABBOTT LABORATORIES | 2002-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020019527-A1 | Substituted phenyl farnesyltransferase inhibitors | FNTA, FNTB, SLC10A1 | FNTA 1/4885FNTB 2/4885PLA2G2A 2995/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.