SCHEMBL7576003

SCHEMBL7576003

COc1ccc(CN(C(C)=O)c2ccccc2Oc2ccccc2)c(OC)c1

nearest known ligand 0.71

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSPO P30536 9/20 0.71
OPRK1 P41145 2/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14542060 0.92 TSPO (0.83) TSPOOPRK1
SCHEMBL14542404 0.90 TSPO (0.88) TSPOOPRK1
SCHEMBL14542291 0.89 TSPO (0.77) TSPOOPRK1
SCHEMBL14542403 0.88 TSPO (0.68) TSPOOPRK1
Ammonia Solution, Strong SCHEMBL7569838 0.88 TSPO (0.75) TSPOOPRK1
SCHEMBL2757556 0.83 TSPO (1.00) TSPOOPRK1
SCHEMBL4190583 0.83 TSPO (1.00) TSPOOPRK1
SCHEMBL14542054 0.83 TSPO (0.62) TSPOOPRK1
SCHEMBL14542064 0.82 TSPO (0.68) TSPOOPRK1
SCHEMBL4234727 0.82 TSPO (1.00) TSPOOPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007036785-A2 CARBON-ISOTOPE MONOXIDE LABELING OF DAA1106 AND ITS ANALOGUES TO BE USED AS TRACERS FOR A PERIPHERAL TYPE BENZODIAZEPINE BINDING SITE GE HEALTHCARE LIMITED (GB) 2007-04-05 WO disclosed
US-6476056-B2 ANTIINFLAMMATORY AGENTS, PSYCHOLOGICAL DISORDERS TAISHO PHARMACEUTICAL CO., LTD. (JP) 2002-11-05 US disclosed
EP-1004573-B1 ARYLOXYANILINE DERIVATIVES TAISHO PHARMACEUTICAL CO LTD (JP) 2002-10-30 EP disclosed
US-20020147191-A1 Aryloxyaniline derivatives NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2002-10-10 US disclosed
US-6333358-B1 AMIDE DERIVATIVES OF ANILINE AS ANTIDEPRESSANTS TAISHO PHARMACEUTICAL CO., LTD. (JP) 2001-12-25 US disclosed
EP-1004573-A1 ARYLOXYANILINE DERIVATIVES TAISHO PHARMACEUTICAL CO., LTD (JP) 2000-05-31 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020147191-A1 Aryloxyaniline derivatives FPR2, ARG2, CYP11B2 TSPO 1248/4885OPRK1 89/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.