Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 9/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | METTL3 | Q86U44 | 2/20 | 0.51 |
| ▸ | TTR | P02766 | 2/20 | 0.51 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.51 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | FABP2 | P12104 | 1/20 | 0.51 |
| ▸ | RXRA | P19793 | 1/20 | 0.51 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.51 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | PDE4A | P27815 | 1/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.51 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.51 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7576888 | 0.84 | CLCN2 (0.50) | MEN1MAPK1KMT2ACLCN2CXCL8 | |
| SCHEMBL7576547 | 0.82 | CLCN2 (0.55) | MEN1KMT2AAKR1C3AKR1C2CLCN2 | |
| SCHEMBL360635 | 0.81 | CXCL8 (0.45) | PTGS2MEN1MAPK1KMT2ATTR | |
| SCHEMBL6809250 | 0.80 | CXCL8 (0.44) | PTGS2MEN1MAPK1KMT2ATTR | |
| SCHEMBL11271011 | 0.80 | CXCL8 (0.44) | PTGS2MEN1MAPK1KMT2ATTR | |
| SCHEMBL2485161 | 0.78 | MEN1 (0.45) | PTGS2MEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL7574624 | 0.78 | ALDH1A1 (0.42) | PTGS2MEN1MAPK1KMT2AMETTL3 | |
| Ammonia Solution, Strong SCHEMBL17997772 | 0.76 | MEN1 (0.44) | PTGS2MEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL28355542 | 0.76 | FPR2 (0.42) | PTGS2MEN1KMT2ATTRAKR1B10 | |
| SCHEMBL7574221 | 0.75 | ALDH1A1 (0.44) | MEN1KMT2AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242069-A2 | ALBUMIN-BINDING COMPOUNDS THAT PREVENT NONENZYMATIC GLYCATION AND THAT MAY BE USED FOR TREATMENT OF GLYCATION-RELATED PATHOLOGIES | EXOCELL, INC. (US) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001003684-A2 | ALBUMIN-BINDING COMPOUNDS THAT PREVENT NONENZYMATIC GLYCATION AND THAT MAY BE USED FOR TREATMENT OF GLYCATION-RELATED PATHOLOGIES | EXOCELL, INC. (US) | 2001-01-18 | — | — | WO | disclosed |